Protein Structure & Regulation  

Our research aim is to answer fundamental questions related to the structure and function of proteins involved in important biochemical processes.

Staff

Publications

2024

Tokatlidis, K. (2024) MIMAS is a new giant multifunctional player in the mitochondrial megacomplex playground. Cell Reports, 43, (doi: 10.1016/j.celrep.2024.113874)

Liu, W., Jenkins, G. (2024) Recent advances in UV-B signalling: Interaction of proteins with the UVR8 photoreceptor. Journal of Experimental Botany, (doi: 10.1093/jxb/erae132)

Pal, S., Nare, Z., Rao, V. A., Smith, B. O., Morrison, I., Fitzgerald, E. A., Scott, A., Bingham, M. J., Pesnot, T. (2024) Accelerating BRPF1b hit identification with BioPhysical and Active Learning Screening (BioPALS) ChemMedChem, 19, (doi: 10.1002/cmdc.202300590)

Nguyen, T.-H., Blatt, M. R. (2024) Surrounded by luxury: the necessities of subsidiary cells. Plant, Cell and Environment, (doi: 10.1111/pce.14872)

Liu, W., Giuriani, G., Havlikova, A., Li, D., Lamont, D. J., Neugart, S., Velanis, C. N., Petersen, J., Hoecker, U., Christie, J. M., Jenkins, G. (2024) Phosphorylation of Arabidopsis UVR8 photoreceptor modulates protein interactions and responses to UV-B radiation. Nature Communications, 15, (doi: 10.1038/s41467-024-45575-7)

Baena, G., Xia, L., Waghmare, S., Yu, Z., Guo, Y., Blatt, M. R., Zhang, B., Karnik, R. (2024) Arabidopsis SNARE SYP132 impacts on PIP2;1 trafficking and function in salinity stress. Plant Journal, (doi: 10.1111/tpj.16649)

Blatt, M. R. (2024) A charged existence: a century of transmembrane ion transport in plants. Plant Physiology, (doi: 10.1093/plphys/kiad630)

2023

Silva-Alvim, F. A.L., Alvim, J. C., Harvey, A., Blatt, M. R. (2023) Speedy stomata of a C4 plant correlate with enhanced K+ channel gating. Plant, Cell and Environment, (doi: 10.1111/pce.14775)

Nguyen, T.-H., Silva-Alvim, F. A. L., Hills, A., Blatt, M. R. (2023) OnGuard3e: a predictive, ecophysiology‐ready tool for gas exchange and photosynthesis research. Plant, Cell and Environment, 46, pp. 3644-3658. (doi: 10.1111/pce.14674)

Quint, M. et al. (2023) 25 years of thermomorphogenesis research: milestones and perspectives. Trends in Plant Science, 28, pp. 1089-1100. (doi: 10.1016/j.tplants.2023.07.001)

Nguyen, T. B.-A., Lefoulon, C., Nguyen, T.-H., Blatt, M. R., Carroll, W. (2023) Engineering stomata for enhanced carbon capture and water-use efficiency. Trends in Plant Science, (doi: 10.1016/j.tplants.2023.06.002)

Karnik, R., Blatt, M. R. (2023) Analyzing protein–protein interactions using the split-ubiquitin system. Humana Press

Agirre, J. et al. (2023) The CCP 4 suite: integrative software for macromolecular crystallography. Acta Crystallographica. Section D: Structural Biology, D79, pp. 449-461. (doi: 10.1107/S2059798323003595)

Horiuchi, K., Uragami, C., Tao, R., Kosumi, D., Cogdell, R. J., Hashimoto, H. (2023) Excited-state dynamics of all the mono-cis and the major di-cis isomers of β-apo-8′-carotenal as revealed by femtosecond time-resolved transient absorption spectroscopy. Molecules, 28, (doi: 10.3390/molecules28114424)

Deni, I. et al. (2023) Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. Cell Chemical Biology, 30, pp. 470-485.e6. (doi: 10.1016/j.chembiol.2023.03.002)

Javitt, A. et al. (2023) The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC. Nature Cancer, 4, pp. 629-647. (doi: 10.1038/s43018-023-00557-4)

Waksman, T., Suetsugu, N., Hermanowicz, P., Ronald, J., Sullivan, S., Łabuz, J., Christie, J. M. (2023) Phototropin phosphorylation of ROOT PHOTOTROPISM 2 and its role in mediating phototropism, leaf positioning and chloroplast accumulation movement in arabidopsis. Plant Journal, 114, pp. 390-402. (doi: 10.1111/tpj.16144)

Cupellini, L., Qian, P., Nguyen-Phan, T. C., Gardiner, A. T., Cogdell, R. J. (2023) Quantum chemical elucidation of a sevenfold symmetric bacterial antenna complex. Photosynthesis Research, 156, pp. 75-87. (doi: 10.1007/s11120-022-00925-8)

Adam, S., Zheng, D., Klein, A., Volz, C., Mullen, W., Shirran, S. L., Smith, B. O., Kalinina, O. V., Müller, R., Koehnke, J. (2023) Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis. Nature Chemistry, 15, pp. 560-568. (doi: 10.1038/s41557-023-01153-w)

Abioye, J., Lawson‐Williams, M., Lecanda, A., Calhoon, B., McQue, A. L., Colloms, S. D., Stark, W. M., Olorunniji, F. J. (2023) High fidelity one‐pot DNA assembly using orthogonal serine integrases. Biotechnology Journal, 18, (doi: 10.1002/biot.202200411)

Lemonidis, K., Rennie, M. L., Arkinson, C., Chaugule, V. K., Clarke, M., Streetley, J., Walden, H. (2023) Structural and biochemical basis of interdependent FANCI-FANCD2 ubiquitination. EMBO Journal, 42, (doi: 10.15252/embj.2022111898)

Gallusci, P., Agius, D. R., Moschou, P. N., Dobránszki, J., Kaiserli, E., Martinelli, F. (2023) Deep inside the epigenetic memories of stressed plants. Trends in Plant Science, 28, pp. 142-153. (doi: 10.1016/j.tplants.2022.09.004)

Cannone, G., Kompaniiets, D., Graham, S., White, M. F., Spagnolo, L. (2023) Structure of the Saccharolobus solfataricus type III-D CRISPR effector. Current Research in Structural Biology, 5, (doi: 10.1016/j.crstbi.2023.100098)

McInnes, K. J., van der Hooft, J. J.J., Sharma, A., Herzyk, P., Hundleby, P. A.C., Schoonbeek, H.-J., Amtmann, A., Ridout, C., Jenkins, G. I. (2023) Overexpression of Brassica napus COMT1 in Arabidopsis heightens UV-B-mediated resistance to Plutella xylostella herbivory. Photochemical and Photobiological Sciences, 22, pp. 2341-2356. (doi: 10.1007/s43630-023-00455-9)

2022

Seale, M., Zhdanov, O., Soons, M. B., Cummins, C., Kroll, E., Blatt, M. R., Zare-Behtash, H., Busse, A., Mastropaolo, E., Bullock, J. M., Viola, I. M., Nakayama, N. (2022) Environmental morphing enables informed dispersal of the dandelion diaspore. eLife, 11, (doi: 10.7554/eLife.81962)

Elvers, I., Nguyen Phan, T. C., Gardiner, A. T., Hunter, C. N., Cogdell, R. J., Köhler, J. (2022) Phasor analysis reveals multicomponent fluorescence kinetics in the LH2 complex from Marichromatium purpuratum. Journal of Physical Chemistry B, 126, pp. 10335-10346. (doi: 10.1021/acs.jpcb.2c04983)

Duan, H.-G., Jha, A., Chen, L., Tiwari, V., Cogdell, R. J., Ashraf, K., Prokhorenko, V. I., Thorwart, M., Miller, R. J. D. (2022) Quantum coherent energy transport in the Fenna–Matthews–Olson complex at low temperature. Proceedings of the National Academy of Sciences of the United States of America, 119, pp. e2212630119. (doi: 10.1073/pnas.2212630119)

Kowalczyk, D., Nakasone, M. A., Smith, B. O., Huang, D. T. (2022) Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function. Life Science Alliance, 5, (doi: 10.26508/lsa.202201472)

Lieberman-Lazarovich, M., Kaiserli, E., Bucher, E., Mladenov, V. (2022) Natural and induced epigenetic variation for crop improvement. Current Opinion in Plant Biology, 70, (doi: 10.1016/j.pbi.2022.102297)

Wu, F., Finkelstein-Shapiro, D., Wang, M., Rosenkampff, I., Yartsev, A., Pascher, T., Nguyen- Phan, T. C., Cogdell, R., Börjesson, K., Pullerits, T. (2022) Optical cavity-mediated exciton dynamics in photosynthetic light harvesting 2 complexes. Nature Communications, 13, (doi: 10.1038/s41467-022-34613-x)

Horaruang, W., Klejchová, M., Carroll, W., Silva-Alvim, F. A.L., Waghmare, S., Papanatsiou, M., Amtmann, A., Hills, A., Alvim, J. C., Blatt, M. R., Zhang, B. (2022) Engineering a K+ channel 'sensory antenna' enhances stomatal kinetics, water use efficiency and photosynthesis. Nature Plants, 8, pp. 1262-1274. (doi: 10.1038/s41477-022-01255-2)

Fang, W., Vellutini, E., Perrella, G., Kaiserli, E. (2022) TANDEM ZINC-FINGER/PLUS3 regulates phytochrome B abundance and signaling to fine-tune hypocotyl growth. Plant Cell, 34, pp. 4213-4231. (doi: 10.1093/plcell/koac236)

Gracie, J., Zamberlan, F., Andrews, I. B., Smith, B. O., Peveler, W. J. (2022) Growth of plasmonic nanoparticles for aging cask-matured whisky. ACS Applied Nano Materials, 5, pp. 15362-15368. (doi: 10.1021/acsanm.2c03406)

Miguel-Romero, L., Alqasmi, M., Bacarizo, J., Tan, J. A., Cogdell, R. J., Chen, J., Byron, O., Christie, G. E., Marina, A., Penadés, J. R. (2022) Non-canonical Staphylococcus aureus pathogenicity island repression. Nucleic Acids Research, 50, pp. 11109-11127. (doi: 10.1093/nar/gkac855)

Qian, P., Nguyen-Phan, T. C., Gardiner, A. T., Croll, T. I., Roszak, A. P., Southall, J., Jackson, P. J., Vasilev, C., Castro-Hartmann, P., Sader, K., Hunter, C. N., Cogdell, R. J. (2022) Cryo-EM structures of light-harvesting 2 complexes from Rhodopseudomonas palustris reveal the molecular origin of absorption tuning. Proceedings of the National Academy of Sciences of the United States of America, 117, (doi: 10.1073/pnas.2210109119)

Patitaki, E., Schivre, G., Zioutopoulou, A., Perrella, G., Bourbousse, C., Barneche, F., Kaiserli, E. (2022) Light, chromatin, action: nuclear events regulating light signaling in Arabidopsis. New Phytologist, 236, pp. 333-349. (doi: 10.1111/nph.18424)

Rennie, M. L., Arkinson, C., Chaugule, V. K., Walden, H. (2022) Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Science Advances, 8, (doi: 10.1126/sciadv.abq6353)

Ryan, S. M., Ruscher, R., Johnston, W. A., Pickering, D. A., Kennedy, M. W., Smith, B. O., Jones, L., Buitrago, G., Field, M. A., Esterman, A. J., McHugh, C. P., Browne, D. J., Cooper, M. M., Ryan, R. Y. M., Doolan, D. L., Engwerda, C. R., Miles, K., Mitreva, M., Croese, J., Rahman, T., Alexandrov, K., Giacomin, P. R., Loukas, A. (2022) Novel antiinflammatory biologics shaped by parasite–host coevolution. Proceedings of the National Academy of Sciences of the United States of America, 119, (doi: 10.1073/pnas.2202795119)

Hogrel, G., Guild, A., Graham, S., Rickman, H., Grüschow, S., Bertrand, Q., Spagnolo, L., White, M. F. (2022) Cyclic nucleotide-induced helical structure activates a TIR immune effector. Nature, 608, pp. 808-812. (doi: 10.1038/s41586-022-05070-9)

Lemonidis, K., Arkinson, C., Rennie, M. L., Walden, H. (2022) Mechanism, specificity and function of FANCD2‐FANCI ubiquitination and deubiquitination. FEBS Journal, 289, pp. 4811-4829. (doi: 10.1111/febs.16077)

Caccavale, E., Johnson, M. P., Brijbassi, S., Andreazza, A. C., Tokatlidis, K. (2022) Mitochondria and Us: from exploration to global collective. Biochemist, 44, pp. 22-28. (doi: 10.1042/bio_2022_122)

Liao, X., Jenkins, G. I. (2022) Cysteines have a role in conformation of the UVR8 photoreceptor. Plant Journal, 111, pp. 583-594. (doi: 10.1111/tpj.15841)

Baena, G., Xia, L., Waghmare, S., Karnik, R. (2022) SNARE SYP132 mediates divergent trafficking of H+-ATPase AHA1 and antimicrobial PR1 during bacterial pathogenesis. Plant Physiology, 189, pp. 1639-1661. (doi: 10.1093/plphys/kiac149)

Kjeldsen, A., Kay, J. E., Baxter, S., McColm, S., Serrano-Amatriain, C., Parker, S., Robb, E., Arnold, S. A., Gilmour, C., Raper, A., Robertson, G., Fleming, R., Smith, B. O., Fotheringham, I. G., Christie, J. M., Magneschi, L. (2022) The fluorescent protein iLOV as a reporter for screening of high‐yield production of antimicrobial peptides in Pichia pastoris. Microbial Biotechnology, 15, pp. 2126-2139. (doi: 10.1111/1751-7915.14034)

Ledahawsky, L. M., Terzenidou, M. E., Edwards, R., Kline, R. A., Graham, L. C., Eaton, S. L., van der Hoorn, D., Chaytow, H., Huang, Y.‐T., Groen, E. J.N., Motyl, A. A. L., Lamont, D. J., Tokatlidis, K., Wishart, T. M., Gillingwater, T. H. (2022) The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo. FEBS Journal, 289, pp. 3894-3914. (doi: 10.1111/febs.16377)

Wang, Y., Karnik, R., Garcia-Mata, C., Hu, H. (2022) Editorial: transport and membrane traffic in stomatal biology. Frontiers in Plant Science, 13, (doi: 10.3389/fpls.2022.898128)

Torres Cabán, C. C., Yang, M., Lai, C., Yang, L., Subach, F. V., Smith, B. O., Piatkevich, K. D., Boyden, E. S. (2022) Tuning the sensitivity of genetically encoded fluorescent potassium indicators through structure-guided and genome mining strategies. ACS Sensors, 7, pp. 1336-1346. (doi: 10.1021/acssensors.1c02201)

Thu, N. B.A., Amtmann, A., Blatt, M. R., Nguyen, T.-H. (2022) Stomata under salt stress—what can mechanistic modeling tell us? Academic Press

Živković, D., Sanchez Dafun, A., Menneteau, T., Schahl, A., Lise, S., Kervarrec, C., Toste Rêgo, A., da Fonseca, P. C. A., Chavent, M., Pineau, C., Burlet-Schiltz, O., Marcoux, J., Bousquet, M.-P. (2022) Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis. Proceedings of the National Academy of Sciences of the United States of America, 119, pp. e2116826119. (doi: 10.1073/pnas.2116826119)

Tibbo, A. J., Mika, D., Dobi, S., Ling, J., McFall, A., Tejeda, G. S., Blair, C., MacLeod, R., MacQuaide, N., Gök, C., Fuller, W., Smith, B. O., Smith, G. L., Vandecasteele, G., Brand, T., Baillie, G. S. (2022) Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins. Journal of Molecular and Cellular Cardiology, 165, pp. 86-102. (doi: 10.1016/j.yjmcc.2022.01.001)

Zioutopoulou, A., Patitaki, E., O'Donnell, L., Kaiserli, E. (2022) Low fluence ultraviolet-B promotes ultraviolet resistance 8-modulated flowering in Arabidopsis. Frontiers in Plant Science, 13, (doi: 10.3389/fpls.2022.840720)

Naqvi, S., He, Q., Trusch, F., Qiu, H., Pham, J., Sun, Q., Christie, J. M., Gilroy, E. M., Birch, P. R.J. (2022) Blue‐light receptor phototropin 1 suppresses immunity to promote Phytophthora infestans infection. New Phytologist, 233, pp. 2282-2293. (doi: 10.1111/nph.17929)

Dunkerley, K. M., Rintala-Dempsey, A. C., Salzano, G., Tadayon, R., Hadi, D., Barber, K. R., Walden, H., Shaw, G. S. (2022) Distinct phosphorylation signals drive acceptor versus free ubiquitin chain targeting by Parkin. Biochemical Journal, 479, pp. 751-766. (doi: 10.1042/bcj20210741)

Guarino, F., Cicatelli, A., Castiglione, S., Agius, D. R., Orhun, G. E., Fragkostefanakis, S., Leclercq, J., Dobránszki, J., Kaiserli, E., Lieberman-Lazarovich, M., Sõmera, M., Sarmiento, C., Vettori, C., Paffetti, D., Poma, A. M. G., Moschou, P. N., Gašparović, M., Yousefi, S., Vergata, C., Berger, M. M. J., Gallusci, P., Miladinović, D., Martinelli, F. (2022) An epigenetic alphabet of crop adaptation to climate change. Frontiers in Genetics, 13, (doi: 10.3389/fgene.2022.818727)

Kim, J., Nguyen-Phan, T. C., Gardiner, A. T., Yoon, T. H., Cogdell, R. J., Cho, M., Scholes, G. D. (2022) Vibrational modes promoting exciton relaxation in the B850 band of LH2. Journal of Physical Chemistry Letters, 13, pp. 1099-1106. (doi: 10.1021/acs.jpclett.1c03868)

Blatt, M. R., Jezek, M., Lew, V. L., Hills, A. (2022) What can mechanistic models tell us about guard cells, photosynthesis, and water use efficiency? Trends in Plant Science, 27, pp. 166-179. (doi: 10.1016/j.tplants.2021.08.010)

Nakasone, M. A., Majorek, K. A., Gabrielsen, M., Sibbet, G. J., Smith, B. O., Huang, D. T. (2022) Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension. Nature Chemical Biology, 18, pp. 422-431. (doi: 10.1038/s41589-021-00952-x)

Neckebroeck, A., Kelly, S. M., Smith, B. O., Clark, J. S. (2022) Synthesis of the prototypical cyclopropyl dipeptide mimic and evaluation of its turn-inducing capability. Journal of Organic Chemistry, 87, pp. 258-270. (doi: 10.1021/acs.joc.1c02344)

Yukihira, N., Uragami, C., Horiuchi, K., Kosumi, D., Gardiner, A. T., Cogdell, R. J., Hashimoto, H. (2022) Intramolecular charge-transfer enhances energy transfer efficiency in carotenoid-reconstituted light-harvesting 1 complex of purple photosynthetic bacteria. Communications Chemistry, 5, (doi: 10.1038/s42004-022-00749-6)

Zhdanov, O., Blatt, M. R., Zare-Behtash, H., Busse, A. (2022) Unidirectional versus bidirectional brushing: simulating wind influence on Arabidopsis thaliana. Quantitative Plant Biology, 3, (doi: 10.1017/qpb.2021.14)

2021

Tokatlidis, K., Eaglesfield, R. (2021) Targeting and insertion of membrane proteins in mitochondria. Frontiers in Cell and Developmental Biology, 9, (doi: 10.3389/fcell.2021.803205)

Blatt, M. (2021) Ae fond fareweel. Plant Physiology, 187, pp. 2341-2343. (doi: 10.1093/plphys/kiab467)

Zioutopoulou, A., Patitaki, E., Xu, T., Kaiserli, E. (2021) The epigenetic mechanisms underlying thermomorphogenesis and heat stress responses in Arabidopsis. Plants, 10, (doi: 10.3390/plants10112439)

Sullivan, S., Waksman, T., Paliogianni, D., Henderson, L., Lütkemeyer, M., Suetsugu, N., Christie, J. M. (2021) Regulation of plant phototropic growth by NPH3/RPT2-like substrate phosphorylation and 14-3-3 binding. Nature Communications, 12, (doi: 10.1038/s41467-021-26333-5)

Prabhakar, A. T., James, C. D., Das, D., Otoa, R., Day, M., Burgner, J., Fontan, C. T., Wang, X., Wieland, A., Donaldson, M. M., Bristol, M. L., Li, R., Oliver, A. W., Pearl, L. H., Smith, B. O., Glass, S., Morgan, I. M. (2021) CK2 phosphorylation of human papillomavirus 16 E2 on serine 23 promotes interaction with TopBP1 and is critical for E2 interaction with mitotic chromatin and the viral life cycle. mBio, 12, (doi: 10.1128/mbio.01163-21)

Jezek, M., Silva-Alvim, F. A.L., Hills, A., Donald, N., Ishka, M. R., Shadbolt, J., He, B., Lawson, T., Harper, J. F., Wang, Y., Lew, V. L., Blatt, M. R. (2021) Guard cell endomembrane Ca2+-ATPases underpin a ‘carbon memory’ of photosynthetic assimilation that impacts on water-use efficiency. Nature Plants, 7, pp. 1301-1313. (doi: 10.1038/s41477-021-00966-2)

Buist, H. K., Luchowska-Stańska, U., van Basten, B., Valli, J., Smith, B. O., Baillie, G. S., Rickman, C., Ricketts, B., Davidson, A., Hannam, R., Sunderland, J., Yarwood, S. J. (2021) Identification and characterization of an affimer affinity reagent for the detection of the cAMP sensor, EPAC1. Cells, 10, (doi: 10.3390/cells10092307)

Geldon, S., Fernandez-Vizarra, E., Tokatlidis, K. (2021) Redox-mediated regulation of mitochondrial biogenesis, dynamics and respiratory chain assembly in yeast and human cells. Frontiers in Cell and Developmental Biology, 9, (doi: 10.3389/fcell.2021.720656)

Kakoulidou, I., Avramidou, E. V., Baránek, M., Brunel-Muguet, S., Farrona, S., Johannes, F., Kaiserli, E., Lieberman-Lazarovich, M., Martinelli, F., Mladenov, V., Testillano, P. S., Vassileva, V., Maury, S. (2021) Epigenetics for crop improvement in times of global change. Biology, 10, (doi: 10.3390/biology10080766)

Kim, J., Nguyen-Phan, T. C., Gardiner, A. T., Cogdell, R. J., Scholes, G. D., Cho, M. (2021) Low-frequency vibronic mixing modulates the excitation energy flow in bacterial light-harvesting complex II. Journal of Physical Chemistry Letters, 12, pp. 6292-6298. (doi: 10.1021/acs.jpclett.1c01782)

Mladenov, V., Fotopoulos, V., Kaiserli, E., Karalija, E., Maury, S., Baranek, M., Segal, N., Testillano, P. S., Vassileva, V., Pinto, G., Nagel, M., Hoenicka, H., Miladinović, D., Gallusci, P., Vergata, C., Kapazoglou, A., Abraham, E., Tani, E., Gerakari, M., Sarri, E., Avramidou, E., Gašparović, M., Martinelli, F. (2021) Deciphering the epigenetic alphabet involved in transgenerational stress memory in crops. International Journal of Molecular Sciences, 22, (doi: 10.3390/ijms22137118)

Morgan, D. C., Morris, C., Mahindra, A., Blair, C. M., Tejeda, G., Herbert, I., Turnbull, M. L., Lieber, G., Willett, B. J., Logan, N., Smith, B., Tobin, A. B., Bhella, D., Baillie, G. S., Jamieson, A. G. (2021) Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalisation. Peptide Science, 113, (doi: 10.1002/pep2.24217)

Diamantopoulou, C., Christoforou, E., Dominoni, D. M., Kaiserli, E., Czyzewski, J., Mirzai, N., Spatharis, S. (2021) Wavelength-dependent effects of artificial light at night on phytoplankton growth and community structure. Proceedings of the Royal Society of London Series B: Biological Sciences, 288, (doi: 10.1098/rspb.2021.0525)

Gundogdu, M., Tadayon, R., Salzano, G., Shaw, G. S., Walden, H. (2021) A mechanistic review of Parkin activation. Biochimica et Biophysica Acta. General Subjects, 1865, (doi: 10.1016/j.bbagen.2021.129894)

Morris, E. P., da Fonseca, P. C.A. (2021) How to build a proteasome. Nature Structural and Molecular Biology, 28, pp. 409-410. (doi: 10.1038/s41594-021-00592-8)

van Beek, L., McClay, É., Patel, S., Schimpl, M., Spagnolo, L., Maia de Oliveira, T. (2021) PARP power: a structural perspective on PARP1, PARP2, and PARP3 in DNA damage repair and nucleosome remodelling. International Journal of Molecular Sciences, 22, (doi: 10.3390/ijms22105112)

Klejchova, M., Silva-Alvim, F. A.L., Blatt, M. R., Alvim, J. C. (2021) Membrane voltage as a dynamic platform for spatio-temporal signalling, physiological and developmental regulation. Plant Physiology, 185, pp. 1523-1541. (doi: 10.1093/plphys/kiab032)

Rennie, M. L., Arkinson, C., Chaugule, V. K., Toth, R., Walden, H. (2021) Structural basis of FANCD2 deubiquitination by USP1-UAF1. Nature Structural and Molecular Biology, 28, pp. 356-364. (doi: 10.1038/s41594-021-00576-8)

Rolczynski, B. S., Yeh, S.-H., Navotnaya, P., Lloyd, L. T., Ginzburg, A. R., Zheng, H., Allodi, M. A., Otto, J. P., Ashraf, K., Gardiner, A. T., Cogdell, R. J., Kais, S., Engel, G. S. (2021) Time-domain line-shape analysis from 2D spectroscopy to precisely determine Hamiltonian parameters for a photosynthetic complex. Journal of Physical Chemistry B, 125, pp. 2812-2820. (doi: 10.1021/acs.jpcb.0c08012)

Christie, J. M., Zurbriggen, M. D. (2021) Optogenetics in plants. New Phytologist, 229, pp. 3108-3115. (doi: 10.1111/nph.17008)

Perrella, G., Zioutopoulou, A., Hamilton, A., Kaiserli, E. (2021) Photobody detection using immunofluorescence and super-resolution imaging in Arabidopsis. Humana

Edwards, R., Eaglesfield, R., Tokatlidis, K. (2021) The mitochondrial intermembrane space: the most constricted mitochondrial sub-compartment with the largest variety of protein import pathways. Open Biology, 11, (doi: 10.1098/rsob.210002)

Zhdanov, O., Blatt, M. R., Zare-Behtash, H., Busse, A. (2021) Wind-evoked anemotropism affects the morphology and mechanical properties of Arabidopsis. Journal of Experimental Botany, 72, pp. 1906-1918. (doi: 10.1093/jxb/eraa541)

Gardiner, A. T., Naydenova, K., Castro-Hartmann, P., Nguyen-Phan, C. T., Russo, C. J., Sader, K., Hunter, C. N., Cogdell, R. J., Qian, P. (2021) The 2.4 Å cryo-EM structure of a heptameric light-harvesting 2 complex reveals two carotenoid energy transfer pathways. Science Advances, 7, (doi: 10.1126/sciadv.abe4650)

Zhang, B., Xia, L., Zhang, Y., Wang, H., Karnik, R. (2021) Tri-SUS: a yeast split-ubiquitin assay to examine protein interactions governed by a third binding partner. Plant Physiology, 185, pp. 285-289. (doi: 10.1093/plphys/kiaa039)

Thyrhaug, E., Schröter, M., Bukartė, E., Kühn, O., Cogdell, R., Hauer, J., Zigmantas, D. (2021) Intraband dynamics and exciton trapping in the LH2 complex of Rhodopseudomonas acidophila. Journal of Chemical Physics, 154, (doi: 10.1063/5.0033802)

Knuhtsen, A., Whiting, R., McWhinnie, F. S., Whitmore, C., Smith, B. O., Green, A. C., Timperley, C. M., Kinnear, K. I., Jamieson, A. G. (2021) μ-conotoxin KIIIA peptidomimetics that block human voltage-gated sodium channels. Peptide Science, 113, (doi: 10.1002/pep2.24203)

Dimogkioka, A.-R., Lees, J., Tokatlidis, K., Lacko, E. (2021) Protein import in mitochondria biogenesis: Guided by targeting signals and sustained by dedicated chaperones. RSC Advances, 11, pp. 32476-32493. (doi: 10.1039/D1RA04497D)

Dickson-Murray, E., Nedara, K., Modjtahedi, N., Tokatlidis, K. (2021) The Mia40/CHCHD4 oxidative folding system: Redox regulation and signaling in the mitochondrial intermembrane space. Antioxidants, 10, (doi: 10.3390/antiox10040592)

2020

Parry, G., Benitez-Alfonso, Y., Gibbs, D. J., Grant, M., Harper, A., Harrison, C. J., Kaiserli, E., Leonelli, S., May, S., McKim, S., Spoel, S., Turnbull, C., van der Hoorn, R. A.L., Murray, J. (2020) How to build an effective research network: lessons from two decades of the GARNet plant science community. Journal of Experimental Botany, 71, pp. 6881-6889. (doi: 10.1093/jxb/eraa397)

Zhdanov, O., Blatt, M. R., Cammarano, A., Zare-Behtash, H., Busse, A. (2020) A new perspective on mechanical characterisation of Arabidopsis stems through vibration tests. Journal of the Mechanical Behavior of Biomedical Materials, 112, (doi: 10.1016/j.jmbbm.2020.104041)

Waraich, N. F., Jain, S., Colloms, S. D., Stark, W. M., Burton, N. P., Maxwell, A. (2020) A novel decatenation assay for DNA topoisomerases using a singly-linked catenated substrate. BioTechniques, 69, pp. 356-362. (doi: 10.2144/btn-2020-0059)

Inoue, S.‐I., Kaiserli, E., Zhao, X., Waksman, T., Takemiya, A., Okumura, M., Takahashi, H., Seki, M., Shinozaki, K., Endo, Y., Sawasaki, T., Kinoshita, T., Zhang, X., Christie, J. M., Shimazaki, K.‐I. (2020) CIPK23 regulates blue light-dependent stomatal opening in Arabidopsis thaliana. Plant Journal, 104, pp. 679-692. (doi: 10.1111/tpj.14955)

de Rooij, P. G.H., Perrella, G., Kaiserli, E., van Zanten, M. (2020) The diverse and unanticipated roles of Histone deacetylase 9 in coordinating plant development and environmental acclimation. Journal of Experimental Botany, 71, pp. 6211-6225. (doi: 10.1093/jxb/eraa335)

Chatrin, C., Gabrielsen, M., Buetow, L., Nakasone, M. A., Ahmed, S. F., Sumpton, D., Sibbet, G. J., Smith, B. O., Huang, D. T. (2020) Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases. Science Advances, 6, (doi: 10.1126/sciadv.abc0418)

Lefoulon, C., Boxall, S. F., Hartwell, J., Blatt, M. R. (2020) Crassulacean acid metabolism guard cell anion channel activity follows transcript abundance and is suppressed by apoplastic malate. New Phytologist, 227, pp. 1847-1857. (doi: 10.1111/nph.16640)

Larson, E. R., Ortmannová, J., Donald, N. A., Alvim, J., Blatt, M. R., Žárský, V. (2020) Synergy among exocyst and SNARE interactions identifies a functional hierarchy in secretion during vegetative growth. Plant Cell, 32, pp. 2951-2963. (doi: 10.1105/tpc.20.00280)

Perrella, G., Zioutopoulou, A., Headland, L. R., Kaiserli, E. (2020) The impact of light and temperature on chromatin organisation and plant adaptation. Journal of Experimental Botany, 71, pp. 5247-5255. (doi: 10.1093/jxb/eraa154)

Mitxitorena, I., Somma, D., Mitchell, J. P., Lepistö, M., Tyrchan, C., Smith, E. L., Kiely, P. A., Walden, H., Keeshan, K., Carmody, R. J. (2020) The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits. Journal of Biological Chemistry, 295, pp. 11754-11763. (doi: 10.1074/jbc.RA120.014113)

Gardiner, A., Nguyen-Phan, T. C., Cogdell, R. J. (2020) A comparative look at structural variation among RC-LH1 ‘core’ complexes present in anoxygenic phototrophic bacteria. Photosynthesis Research, 145, pp. 83-96. (doi: 10.1007/s11120-020-00758-3)

Jezek, M., Hills, A., Blatt, M. R., Lew, V. L. (2020) A constraint-relaxation-recovery mechanism for stomatal dynamics. Plant, Cell and Environment, 42, pp. 2399-2410. (doi: 10.1111/pce.13568)

Liao, X., Liu, W., Yang, H.-Q., Jenkins, G. I. (2020) A dynamic model of UVR8 photoreceptor signaling in UV-B acclimated Arabidopsis. New Phytologist, 227, pp. 857-866. (doi: 10.1111/nph.16581)

Rennie, M. L., Lemonidis, K., Arkinson, C., Chaugule, V. K., Clarke, M., Streetley, J., Spagnolo, L., Walden, H. (2020) Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA. EMBO Reports, 21, (doi: 10.15252/embr.202050133)

Flütsch, S., Wang, Y., Takemiya, A., Vialet-Chabrand, S. R., Klejchova, M., Nigro, A., Hills, A., Lawson, T., Blatt, M. R., Santelia, D. (2020) Guard cell starch degradation yields glucose for rapid stomatal opening in Arabidopsis. Plant Cell, 32, pp. 2325-2344. (doi: 10.1105/tpc.18.00802)

Perrella, G., Vellutini, E., Zioutopoulou, A., Patitaki, E., Headland, L. R., Kaiserli, E. (2020) Let it bloom: crosstalk between light and flowering signalling in Arabidopsis. Physiologia Plantarum, 169, pp. 301-311. (doi: 10.1111/ppl.13073)

Arp, T. B., Kistner-Morris, J., Aji, V., Cogdell, R. J., van Grondelle, R., Gabor, N. M. (2020) Quieting a noisy antenna reproduces photosynthetic light-harvesting spectra. Science, 368, pp. 1490-1495. (doi: 10.1126/science.aba6630)

Frost, M. G., Mazloumi Aboukheili, A. M., Toth, R., Walden, H. (2020) Characterisation of FANCL variants observed in patient cancer cells. Bioscience Reports, 40, (doi: 10.1042/BSR20191304)

Reinhardt, C., Arena, G., Nedara, K., Edwards, R., Brenner, C., Tokatlidis, K., Modjtahedi, N. (2020) AIF meets the CHCHD4/Mia40-dependent mitochondrial import pathway. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1866, (doi: 10.1016/j.bbadis.2020.165746)

Rennie, M. L., Chaugule, V. K., Walden, H. (2020) Modes of allosteric regulation of the ubiquitination machinery. Current Opinion in Structural Biology, 62, pp. 189-196. (doi: 10.1016/j.sbi.2020.02.003)

Klejchová, M., Hills, A., Blatt, M. R. (2020) Predicting the unexpected in stomatal gas exchange: not just an open-and-shut case. Biochemical Society Transactions, 48, pp. 881-889. (doi: 10.1042/BST20190632)

Crecente Garcia, S., Neckebroeck, A., Clark, J. S., Smith, B. O., Thomson, A. R. (2020) β-turn mimics by chemical ligation. Organic Letters, 22, pp. 4424-4428. (doi: 10.1021/acs.orglett.0c01427)

Edwards, R., Gerlich, S., Tokatlidis, K. (2020) The biogenesis of mitochondrial intermembrane space proteins. Biological Chemistry, 401, pp. 737-747. (doi: 10.1515/hsz-2020-0114)

Gellings, E., Cogdell, R. J., van Hulst, N. F. (2020) Room-temperature excitation-emission spectra of single LH2 complexes show remarkably little variation. Journal of Physical Chemistry Letters, 11, pp. 2430-2435. (doi: 10.1021/acs.jpclett.0c00375)

Xia, L., Marquès-Bueno, M. M., Karnik, R. (2020) Trafficking SNARE SYP132 partakes in auxin-associated root growth. Plant Physiology, 182, pp. 1836-1840. (doi: 10.1104/pp.19.01301)

Chaugule, V. K., Arkinson, C., Rennie, M. L., Kämäräinen, O., Toth, R., Walden, H. (2020) Allosteric mechanism for site-specific ubiquitination of FANCD2. Nature Chemical Biology, 16, pp. 291-301. (doi: 10.1038/s41589-019-0426-z)

Voigt, S., Sterz, K. R., Giehler, F., Mohr, A.-W., Wilson, J. B., Moosmann, A., Kieser, A. (2020) A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation. Nature Communications, 11, (doi: 10.1038/s41467-020-14502-x)

Visentin, S., Cannone, G., Doutch, J., Harris, G., Gleghorn, M. L., Clifton, L., Smith, B. O., Spagnolo, L. (2020) A multi-pronged approach to understanding the form and function of hStaufen protein. RNA, 26, pp. 265-277. (doi: 10.1261/rna.072595.119)

Horaruang, W., Hills, A., Blatt, M. R. (2020) Communication between the plasma membrane and tonoplast is an emergent property of ion transport. Plant Physiology, 182, pp. 1833-1835. (doi: 10.1104/pp.19.01485)

2019

van der Woude, L. C., Perrella, G., Snoek, B. L., van Hoogdalem, M., Novák, O., van Verk, M. C., van Kooten, H. N., Zorn, L. E., Tonckens, R., Dongus, J. A., Praat, M., Stouten, E. A., Proveniers, M. C. G., Vellutini, E., Patitaki, E., Shapulatov, U., Kohlen, W., Balasubramanian, S., Ljung, K., van der Krol, A. R., Smeekens, S., Kaiserli, E., van Zanten, M. (2019) HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in Arabidopsis thaliana by mediating H2A.Z depletion. Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 25343-25354. (doi: 10.1073/pnas.1911694116)

Gundogdu, M., Walden, H. (2019) Structural basis of generic versus specific E2-RING E3 interactions in protein ubiquitination. Protein Science, 28, pp. 1758-1770. (doi: 10.1002/pro.3690)

Waghmare, S., Lefoulon, C., Zhang, B., Lileikyte, E., Donald, N., Blatt, M. (2019) K+ channel and SEC11 binding exchange regulates SNARE assembly for secretory traffic. Plant Physiology, 181, pp. 1096-1113. (doi: 10.1104/pp.19.00919)

Taffet, E. J., Lee, B. G., Toa, Z. S. D., Pace, N., Rumbles, G., Southall, J., Cogdell, R. J., Scholes, G. D. (2019) Carotenoid nuclear reorganization and interplay of bright and dark excited states. Journal of Physical Chemistry B, 123, pp. 8628-8643. (doi: 10.1021/acs.jpcb.9b04027)

Zhdanov, O., Busse, A., Cammarano, A., Zare-Behtash, H., Blatt, M. (2019) Effect of Wind on Morphology and Mechanical Properties of Arabidopsis Thaliana.

Toste Rêgo, A., da Fonseca, P. C.A. (2019) Characterization of fully recombinant human 20S and 20S-PA200 proteasome complexes. Molecular Cell, 76, pp. 138-147.e5. (doi: 10.1016/j.molcel.2019.07.014)

Sharma, A., Sharma, B., Hayes, S., Kerner, K., Hoecker, U., Jenkins, G. I., Franklin, K. A. (2019) UVR8 disrupts stabilisation of PIF5 by COP1 to inhibit plant stem elongation in sunlight. Nature Communications, 10, (doi: 10.1038/s41467-019-12369-1)

Karki, K. J., Chen, J., Sakurai, A., Shi, Q., Gardiner, A. T., Kühn, O., Cogdell, R. J., Pullerits, T. (2019) Before Förster. Initial excitation in photosynthetic light harvesting. Chemical Science, 10, pp. 7923-7928. (doi: 10.1039/C9SC01888C)

Fillol-Salom, A., Bacarizo Roa, J. L., Alqasmi, M. H. H., Ciges-Tomas, J. R., Martínez-Rubio, R., Roszak, A. W., Cogdell, R. J., Chen, J., Marina, A., Penades, J. R. (2019) Hijacking the hijackers: Escherichia coli pathogenicity islands redirect helper phage packaging for their own benefit. Molecular Cell, 75, pp. 1020-1030.e4. (doi: 10.1016/j.molcel.2019.06.017)

Jurić, I., Hibberd, J. M., Blatt, M., Burroughs, N. J. (2019) Computational modelling predicts substantial carbon assimilation gains for C3 plants with a single-celled C4 biochemical pump. PLoS Computational Biology, 15, (doi: 10.1371/journal.pcbi.1007373)

Ibáñez-Shimabukuro, M., Rey-Burusco, M. F., Gabrielsen, M., Franchini, G. R., Riboldi-Tunnicliffe, A., Roe, A. J., Griffiths, K., Cooper, A., Córsico, B., Kennedy, M. W., Smith, B. O. (2019) Structure and ligand binding of As-p18, an extracellular fatty acid binding protein from the eggs of a parasitic nematode. Bioscience Reports, 39, (doi: 10.1042/BSR20191292)

Caceres, C., Spatharis, S., Kaiserli, E., Smeti, E., Flowers, H., Bonachela, J. A. (2019) Temporal phosphate gradients reveal diverse acclimation responses in phytoplankton phosphate uptake. ISME Journal, 13, pp. 2834-2845. (doi: 10.1038/s41396-019-0473-1)

O'Hara, A., Headland, L. R., Díaz-Ramos, L. A., Morales, L. O., Strid, Å., Jenkins, G. I. (2019) Regulation of Arabidopsis gene expression by low fluence rate UV-B independently of UVR8 and stress signaling. Photochemical and Photobiological Sciences, 18, pp. 1675-1684. (doi: 10.1039/C9PP00151D)

Hart, J. E., Sullivan, S., Hermanowicz, P., Petersen, J., Diaz-Ramos, L. A., Hoey, D. J., Łabuz, J., Christie, J. M. (2019) Engineering the phototropin photocycle improves photoreceptor performance and plant biomass production. Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 12550-12557. (doi: 10.1073/pnas.1902915116)

Blackman, M. J., Stokes, B. H., Yoo, E., Murithi, J. M., Luth, M. R., Afanasyev, P., da Fonseca, P. C.A., Winzeler, E. A., Ng, C. L., Bogyo, M., Fidock, D. A. (2019) Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents. PLoS Pathogens, 15, (doi: 10.1371/journal.ppat.1007722)

Sullivan, S., Kharshiing, E., Laird, J., Sakai, T., Christie, J. M. (2019) Deetiolation enhances phototropism by modulating NON-PHOTOTROPIC HYPOCOTYL3 phosphorylation status. Plant Physiology, 180, pp. 1119-1131. (doi: 10.1104/pp.19.00206)

Xia, L., Marques-Bueno, M. M., Bruce, C. G., Karnik, R. (2019) Unusual roles of secretory SNARE SYP132 in plasma membrane H+-ATPase traffic and vegetative plant growth. Plant Physiology, 180, pp. 837-858. (doi: 10.1104/pp.19.00266)

Zhao, J., Pokhilko, A., Ebenhöh, O., Rosser, S. J., Colloms, S. D. (2019) A single-input binary counting module based on serine integrase site-specific recombination. Nucleic Acids Research, 47, pp. 4896-4909. (doi: 10.1093/nar/gkz245)

Zhang, B., Karnik, R., Alvim, J., Donald, N., Blatt, M. R. (2019) Dual sites for SEC11 on the SNARE SYP121 implicate a binding exchange during secretory traffic. Plant Physiology, 180, pp. 228-239. (doi: 10.1104/pp.18.01315)

Rühl, J., Citterio, C., Engelmann, C., Haigh, T., Dzionek, A., Dreyer, J., Khanna, R., Taylor, G. S., Wilson, J. B., Leung, C. S., Munz, C. (2019) Heterologous prime-boost vaccination protects against EBV antigen–expressing lymphomas. Journal of Clinical Investigation, 129, pp. 2071-2087. (doi: 10.1172/JCI125364)

Ji, H., Wang, S., Cheng, C., Li, R., Wang, Z., Jenkins, G. I., Kong, F., Li, X. (2019) The RCC 1 family protein SAB 1 negatively regulates ABI 5 through multidimensional mechanisms during postgermination in Arabidopsis. New Phytologist, 222, pp. 907-922. (doi: 10.1111/nph.15653)

Papanatsiou, M., Petersen, J., Henderson, L., Wang, Y., Christie, J.M., Blatt, M.R. (2019) Optogenetic manipulation of stomatal kinetics improves carbon assimilation, water use, and growth. Science, 363, pp. 1456-1459. (doi: 10.1126/science.aaw0046)

Edwards, R., Tokatlidis, K. (2019) The yeast voltage-dependent anion channel Porin: more IMPORTant than just metabolite transport. Molecular Cell, 73, pp. 861-862. (doi: 10.1016/j.molcel.2019.02.028)

Conte, E., Mende, L., Grainge, I., Colloms, S. D. (2019) A mini-ISY100 transposon delivery system effective in γ proteobacteria. Frontiers in Microbiology, 10, (doi: 10.3389/fmicb.2019.00280)

Zhao, C. et al. (2019) Evolution of chloroplast retrograde signaling facilitates green plant adaptation to land. Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 5015-5020. (doi: 10.1073/pnas.1812092116)

Knuhtsen, A., Whitmore, C., McWhinnie, F. S., McDougall, L., Whiting, R., Smith, B. O., Timperley, C. M., Green, A. C., Kinnear, K. I., Jamieson, A. G. (2019) α-conotoxin GI triazole-peptidomimetics: potent and stable blockers of a human acetylcholine receptor. Chemical Science, 10, pp. 1671-1676. (doi: 10.1039/C8SC04198A)

Liao, X., Zhang, B., Blatt, M. R., Jenkins, G. I. (2019) A FRET method for investigating dimer/monomer status and conformation of the UVR8 photoreceptor. Photochemical and Photobiological Sciences, 18, pp. 367-374. (doi: 10.1039/C8PP00489G)

Camacho, I. S., Theisen, A., Johannissen, L. O., Díaz-Ramos, L. A., Christie, J. M., Jenkins, G. I., Bellina, B., Barran, P., Jones, A. R. (2019) Native mass spectrometry reveals the conformational diversity of the UVR8 photoreceptor. Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 1116-1125. (doi: 10.1073/pnas.1813254116)

Robson, T. M., Aphalo, P. J., Banaś, A. K., Barnes, P. W., Brelsford, C. C., Jenkins, G. I., Kotilainen, T. K., Łabuz, J., Martínez-Abaigar, J., Morales, L. O., Neugart, S., Pieristè, M., Rai, N., Vandenbussche, F., Jansen, M. A. K. (2019) A perspective on ecologically relevant plant-UV research and its practical application. Photochemical and Photobiological Sciences, 18, pp. 970-988. (doi: 10.1039/c8pp00526e)

Kunsel, T., Tiwari, V., Matutes, Y. A., Gardiner, A. T., Cogdell, R. J., Ogilvie, J. P., Jansen, T. L. C. (2019) Simulating fluorescence-detected two-dimensional electronic spectroscopy of multichromophoric systems. Journal of Physical Chemistry B, 123, pp. 394-406. (doi: 10.1021/acs.jpcb.8b10176)

Chaugule, V. K., Arkinson, C., Toth, R., Walden, H. (2019) Enzymatic preparation of monoubiquitinated FANCD2 and FANCI proteins. Elsevier

Purohit, P. K., Edwards, R., Tokatlidis, K., Saini, N. (2019) MiR-195 regulates mitochondrial function by targeting mitofusin-2 in breast cancer cells. RNA Biology, 16, pp. 918-929. (doi: 10.1080/15476286.2019.1600999)

2018

Jackson, M., Marks, L., May, G. H.W., Wilson, J. B. (2018) The genetic basis of disease. Essays In Biochemistry, 62, pp. 643-723. (doi: 10.1042/EBC20170053)

Waghmare, S., Lileikyte, E., Karnik, R., Goodman, J. K., Blatt, M. R., Jones, A. M.E. (2018) SNAREs SYP121 and SYP122 mediate the secretion of distinct cargo subsets. Plant Physiology, 178, pp. 1679-1688. (doi: 10.1104/pp.18.00832)

Condos, T. E.C., Dunkerley, K. M., Freeman, E. A., Barber, K. R., Aguirre, J. D., Chaugule, V. K., Xiao, Y., Konermann, L., Walden, H., Shaw, G. S. (2018) Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation. EMBO Journal, (doi: 10.15252/embj.2018100014)

Lefoulon, C., Waghmare, S., Karnik, R., Blatt, M. R. (2018) Gating control and K+ uptake by the KAT1 K+ channel leaveraged through membrane anchoring of the trafficking protein SYP121. Plant, Cell and Environment, 41, pp. 2668-2677. (doi: 10.1111/pce.13392)

Arkinson, C., Chaugule, V. K., Toth, R., Walden, H. (2018) Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1. Life Science Alliance, 1, (doi: 10.26508/lsa.201800162)

Tiwari, V., Matutes, Y. A., Gardiner, A. T., Jansen, T. L. C., Cogdell, R. J., Ogilvie, J. P. (2018) Spatially-resolved fluorescence-detected two-dimensional electronic spectroscopy probes varying excitonic structure in photosynthetic bacteria. Nature Communications, 9, (doi: 10.1038/s41467-018-06619-x)

Kaiserli, E., Perrella, G., Davidson, M. L.H. (2018) Light and temperature shape nuclear architecture and gene expression. Current Opinion in Plant Biology, 45, pp. 103-111. (doi: 10.1016/j.pbi.2018.05.018)

Zhang, B., Karnik, R., Donald, N., Blatt, M. R. (2018) A GPI signal peptide-anchored split-ubiquitin (GPS) system for detecting soluble bait protein interactions at the membrane. Plant Physiology, 178, pp. 13-17. (doi: 10.1104/pp.18.00577)

Niedzwiedzki, D. M., Gardiner, A. T., Blankenship, R. E., Cogdell, R. J. (2018) Energy transfer in purple bacterial photosynthetic units from cells grown in various light intensities. Photosynthesis Research, 137, pp. 389-402. (doi: 10.1007/s11120-018-0512-1)

Díaz-Ramos, L. A., O'Hara, A., Kanagarajan, S., Farkas, D., Strid, Å., Jenkins, G. I. (2018) Difference in the action spectra for UVR8 monomerisation and HY5 transcript accumulation in Arabidopsis. Photochemical and Photobiological Sciences, 17, pp. 1108-1117. (doi: 10.1039/C8PP00138C)

Agliassa, C., Narayana, R., Christie, J. M., Maffei, M. E. (2018) Geomagnetic field impacts on cryptochrome and phytochrome signaling. Journal of Photochemistry and Photobiology B: Biology, 185, pp. 32-40. (doi: 10.1016/j.jphotobiol.2018.05.027)

Sonani, R. R., Gardiner, A., Rastogi, R. P., Cogdell, R., Robert, B., Madamwar, D. (2018) Site, trigger, quenching mechanism and recovery of non-photochemical quenching in cyanobacteria: recent updates. Photosynthesis Research, 137, pp. 171-180. (doi: 10.1007/s11120-018-0498-8)

Nottoli, M., Jurinovich, S., Cupellini, L., Gardiner, A. T., Cogdell, R., Mennucci, B. (2018) The role of charge-transfer states in the spectral tuning of antenna complexes of purple bacteria. Photosynthesis Research, 137, pp. 215-226. (doi: 10.1007/s11120-018-0492-1)

Feroz, H., Ferlez, B., Lefoulon, C., Ren, T., Baker, C. S., Gajewski, J. P., Lugar, D. J., Gaudana, S. B., Butler, P. J., Hühn, J., Lamping, M., Parak, W. J., Hibberd, J. M., Kerfeld, C. A., Smirnoff, N., Blatt, M. R., Golbeck, J. H., Kumar, M. (2018) Light-driven chloride transport kinetics of halorhodopsin. Biophysical Journal, 115, pp. 353-360. (doi: 10.1016/j.bpj.2018.06.009)

Homans, R. J., Khan, R. U., Andrews, M. B., Kjeldsen, A. E., Natrajan, L. S., Marsden, S., McKenzie, E. A., Christie, J. M., Jones, A. R. (2018) Two photon spectroscopy and microscopy of the fluorescent flavoprotein, iLOV. Physical Chemistry Chemical Physics, 20, pp. 16949-16955. (doi: 10.1039/c8cp01699b)

Tokatlidis, K. (2018) Shaping the import system of mitochondria. eLife, 7, (doi: 10.7554/elife.38209)

Xue, Y., Xing, J., Wan, Y., Lv, X., Fan, L., Zhang, Y., Song, K., Wang, L., Wang, X., Deng, X., Baluska, F., Christie, J. M., Lin, J. (2018) Arabidopsis blue light receptor phototropin 1 undergoes blue light-induced activation in membrane microdomains. Molecular Plant, 11, pp. 846-859. (doi: 10.1016/j.molp.2018.04.003)

Cardenas-Rodriguez, M., Chatzi, A., Tokatlidis, K. (2018) Iron–sulfur clusters: from metals through mitochondria biogenesis to disease. Journal of Biological Inorganic Chemistry, 23, pp. 509-520. (doi: 10.1007/s00775-018-1548-6)

Pokhilko, A., Ebenhöh, O., Stark, W. M., Colloms, S. D. (2018) Mathematical model of a serine integrase-controlled toggle switch with a single input. Journal of the Royal Society: Interface, 15, (doi: 10.1098/rsif.2018.0160)

Walden, H., Rittinger, K. (2018) RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns. Nature Structural and Molecular Biology, 25, pp. 440-445. (doi: 10.1038/s41594-018-0063-3)

Zhdanov, O., Busse, A., Blatt, M., Zare-Behtash, H. (2018) A specialised wind tunnel for investigation of ecophysiological response of plants to wind.

Bustos, F., Segarra-Fas, A., Chaugule, V. K., Brandenburg, L., Branigan, E., Toth, R., Macartney, T., Knebel, A., Hay, R. T., Walden, H., Findlay, G. M. (2018) RNF12 X-linked intellectual disability mutations disrupt E3 ligase activity and neural differentiation. Cell Reports, 23, pp. 1599-1611. (doi: 10.1016/j.celrep.2018.04.022)

Perrella, G., Davidson, M. L.H., O'Donnell, L., Nastase, A.-M., Herzyk, P., Breton, G., Pruneda-Paz, J. L., Kay, S. A., Chory, J., Kaiserli, E. (2018) ZINC-FINGER interactions mediate transcriptional regulation of hypocotyl growth in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America, 115, pp. E4503-E4511. (doi: 10.1073/pnas.1718099115)

Armfield, K., Baillie, G., Wilson, J.B. (2018) Development of Therapeutic Approaches to Targeting Epstein-Barr virus Related Malignancies.

Alqarni, S., Wilson, J.B. (2018) Epstein-Barr Virus Nuclear Antigen-1, Action and Reaction as an Oncogene.

Kosumi, D., Nishiguchi, T., Amao, Y., Cogdell, R.J., Hashimoto, H. (2018) Singlet and triplet excited states dynamics of photosynthetic pigment chlorophyll a investigated by sub-nanosecond pump-probe spectroscopy. Journal of Photochemistry and Photobiology A: Chemistry, 358, pp. 374-378. (doi: 10.1016/j.jphotochem.2017.09.046)

Arkinson, C., Walden, H. (2018) Parkin function in Parkinson's disease. Science, 360, pp. 267-268. (doi: 10.1126/science.aar6606)

Blatt, M. R. (2018) Concepts and techniques in plant membrane physiology. John Wiley & Sons, Ltd

Christie, J. M. (2018) Phototropins and other LOV-containing proteins. John Wiley & Sons, Ltd

Blatt, M.R., Thiel, G. (2018) SNARE components and mechanisms of exocytosis in plants. John Wiley & Sons, Ltd

Jenkins, G. I., Brown, B. A. (2018) UV-B perception and signal transduction. John Wiley & Sons, Ltd

Schnabel, J., Hombach, P., Waksman, T., Guiriani, G., Petersen, J., Christie, J. M. (2018) A chemical genetic approach to engineer phototropin kinases for substrate labeling. Journal of Biological Chemistry, 293, pp. 5613-5623. (doi: 10.1074/jbc.RA118.001834)

Wilson, J. B., Manet, E., Gruffat, H., Busson, P., Blondel, M., Fahraeus, R. (2018) EBNA1: oncogenic activity, immune evasion and biochemical functions provide targets for novel therapeutic strategies against Epstein-Barr virus-associated cancers. Cancers, 10, (doi: 10.3390/cancers10040109)

Gardiner, A. T., Niedzwiedzki, D. M., Cogdell, R. J. (2018) Adaptation of Rhodopseudomonas acidophila strain 7050 to growth at different light intensities: what are the benefits to changing the type of LH2? Faraday Discussions, 207, pp. 471-489. (doi: 10.1039/C7FD00191F)

Egea, J. et al. (2018) Corrigendum to “European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” [Redox Biol. 13 (2017) 94–162] Redox Biology, 14, pp. 694-696. (doi: 10.1016/j.redox.2017.10.001)

Hashimoto, H., Uragami, C., Yukihira, N., Gardiner, A. T., Cogdell, R. J. (2018) Understanding/unravelling carotenoid excited singlet states. Journal of the Royal Society: Interface, 15, (doi: 10.1098/rsif.2018.0026)

Schröter, M., Alcocer, M. J.P., Cogdell, R. J., Kühn, O., Zigmantas, D. (2018) Origin of the two bands in the B800 ring and their involvement in the energy transfer network of Allochromatium vinosum. Journal of Physical Chemistry Letters, 9, pp. 1340-1345. (doi: 10.1021/acs.jpclett.8b00438)

Sonani, R. R., Roszak, A. W., de Percin Northumberland, C. O., Madamwar, D., Cogdell, R. J. (2018) An improved crystal structure of C-phycoerythrin from the marine cyanobacterium Phormidium sp. A09DM. Photosynthesis Research, 135, pp. 65-78. (doi: 10.1007/s11120-017-0443-2)

Southall, J., Henry, S. L., Gardiner, A. T., Roszak, A. W., Mullen, W., Carey, A.-M., Kelly, S. M., de Percin Northumberland, C. O., Cogdell, R. J. (2018) Characterisation of a pucBA deletion mutant from Rhodopseudomonas palustris lacking all but the pucBAd genes. Photosynthesis Research, 135, pp. 9-21. (doi: 10.1007/s11120-017-0386-7)

Kowalska, D., Szalkowski, M., Ashraf, K., Grzelak, J., Lokstein, H., Niedziolka-Jonsson, J., Cogdell, R., Mackowski, S. (2018) Spectrally selective fluorescence imaging of Chlorobaculum tepidum reaction centers conjugated to chelator-modified silver nanowires. Photosynthesis Research, 135, pp. 329-336. (doi: 10.1007/s11120-017-0455-y)

Kaiserli, E. (2018) Ultraviolet rays light up transcriptional networks regulating plant growth. Developmental Cell, 44, pp. 409-411. (doi: 10.1016/j.devcel.2018.02.005)

Kawamoto, K., Tamiya, Y., Storr, T., Cogdell, R. J., Kinoshita, I., Hashimoto, H. (2018) Disentangling the 1MLCT transition of [Ru(bpy)3]2+ by Stark absorption spectroscopy. Journal of Photochemistry and Photobiology A: Chemistry, 353, pp. 618-624. (doi: 10.1016/j.jphotochem.2017.08.025)

Cogdell, R. J., Gardiner, A. T., Yukihira, N., Hashimoto, H. (2018) Solar fuels and inspiration from photosynthesis. Journal of Photochemistry and Photobiology A: Chemistry, 353, pp. 645-653. (doi: 10.1016/j.jphotochem.2017.09.013)

Malý, P., Gardiner, A. T., Cogdell, R. J., van Grondelle, R., Mančal, T. (2018) Robust light harvesting by a noisy antenna. Physical Chemistry Chemical Physics, 20, pp. 4360-4372. (doi: 10.1039/c7cp06139k)

Christie, J. M., Suetsugu, N., Sullivan, S., Wada, M. (2018) Shining light on the function of NPH3/RPT2-like proteins in phototropin signalling. Plant Physiology, 176, pp. 1015-1024. (doi: 10.1104/pp.17.00835)

Rolczynski, B. S., Zheng, H., Singh, V. P., Navotnaya, P., Ginzburg, A. R., Caram, J. R., Ashraf, K., Gardiner, A. T., Yeh, S.-H., Kais, S., Cogdell, R. J., Engel, G. S. (2018) Correlated protein environments drive quantum coherence lifetimes in photosynthetic pigment-protein complexes. Chem, 4, pp. 138-149. (doi: 10.1016/j.chempr.2017.12.009)

Löhner, A., Cogdell, R., Köhler, J. (2018) Contribution of low-temperature single-molecule techniques to structural issues of pigment-protein complexes from photosynthetic purple bacteria. Journal of the Royal Society: Interface, 15, (doi: 10.1098/rsif.2017.0680)

Soriano, G., Cloix, C., Heilmann, M., Núñez-Olivera, E., Martínez-Abaigar, J., Jenkins, G. I. (2018) Evolutionary conservation of structure and function of the UVR8 photoreceptor from the liverwort Marchantia polymorpha and the moss Physcomitrella patens. New Phytologist, 217, pp. 151-162. (doi: 10.1111/nph.14767)

Pantin, F., Blatt, M. R. (2018) Stomatal response to humidity: blurring the boundary between active and passive movement. Plant Physiology, 176, pp. 485-488. (doi: 10.1104/pp.17.01699)

AlQarni, S., Al-Sheikh, Y., Campbell, D., Drotar, M., Hannigan, A., Boyle, S., Herzyk, P., Kossenkov, A., Armfield, K., Jamieson, L., Bailo, M., Lieberman, P. M., Tsimbouri, P., Wilson, J. B. (2018) Lymphomas driven by Epstein-Barr virus nuclear antigen-1 (EBNA1) are dependant upon Mdm2. Oncogene, 37, pp. 3998-4012. (doi: 10.1038/s41388-018-0147-x)

2017

Gnanasundram, S. V., Pyndiah, S., Daskalogianni, C., Armfield, K., Nylander, K., Wilson, J. B., Fåhraeus, R. (2017) PI3Kδ activates E2F1 synthesis in response to mRNA translation stress. Nature Communications, 8, (doi: 10.1038/s41467-017-02282-w)

Gao, X., Lampraki, E.-M., Al-Khalidi, S., Qureshi, M. A., Desai, R., Wilson, J. B. (2017) N-acetylcysteine (NAC) ameliorates Epstein-Barr virus latent membrane protein 1 induced chronic inflammation. PLoS ONE, 12, (doi: 10.1371/journal.pone.0189167)

Cooper, A., Vance, S. J., Smith, B. O., Kennedy, M. W. (2017) Frog foams and natural protein surfactants. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 534, pp. 120-129. (doi: 10.1016/j.colsurfa.2017.01.049)

Jenkins, G. I. (2017) Photomorphogenic responses to ultraviolet-B light. Plant, Cell and Environment, 40, pp. 2544-2557. (doi: 10.1111/pce.12934)

Wang, Y., Hills, A., Vialet-Chabrand, S., Papanatsiou, M., Griffiths, H., Rogers, S., Lawson, T., Lew, V. L., Blatt, M. R. (2017) Unexpected connections between humidity and ion transport discovered using a model to bridge guard cell-to-leaf scales. Plant Cell, 29, pp. 2921-2939. (doi: 10.1105/tpc.17.00694)

Kell, A., Jassas, M., Hacking, K., Cogdell, R. J., Jankowiak, R. (2017) On light-induced photoconversion of B800 bacteriochlorophylls in the LH2 antenna of the purple sulfur bacterium Allochromatium vinosum. Journal of Physical Chemistry B, 121, pp. 9999-10006. (doi: 10.1021/acs.jpcb.7b06185)

Gabrielsen, M., Buetow, L., Nakasone, M. A., Ahmed, S. F., Sibbet, G. J., Smith, B. O., Zhang, W., Sidhu, S. S., Huang, D. T. (2017) A general strategy for discovery of inhibitors and activators of RING and U-box E3 ligases with ubiquitin variants. Molecular Cell, 68, pp. 456-470.e10. (doi: 10.1016/j.molcel.2017.09.027)

Morreale, F. E., Testa, A., Chaugule, V. K., Bortoluzzi, A., Ciulli, A., Walden, H. (2017) Mind the metal: a fragment library-derived zinc impurity binds the E2 ubiquitin-conjugating enzyme Ube2T and induces structural rearrangements. Journal of Medicinal Chemistry, 60, pp. 8183-8191. (doi: 10.1021/acs.jmedchem.7b01071)

Larson, E. R., Van Zelm, E., Roux, C., Marion-Poll, A., Blatt, M. R. (2017) Clathrin Heavy Chain subunits coordinate endo- and exocytic traffic and affect stomatal movement. Plant Physiology, 175, pp. 708-720. (doi: 10.1104/pp.17.00970)

Egea, J. et al. (2017) European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) Redox Biology, 13, pp. 94-162. (doi: 10.1016/j.redox.2017.05.007)

Symes, M., Cogdell, R., Macdonald, L., McGlynn, J., Irvine, N., Alshibane, I., Bloor, L., Rausch, B., Hargreaves, J. S.J., Cronin, L. (2017) Using earth abundant materials for the catalytic evolution of hydrogen from electron-coupled proton buffers. Sustainable Energy and Fuels, 1, pp. 1782-1787. (doi: 10.1039/C7SE00334J)

Magennis, S., Toulmin, A., Baltierra-Jasso, L. E., Morten, M. J., Sabir, T., McGlynn, P., Schröder, G. F., Smith, B. O., Magennis, S. W. (2017) Conformational heterogeneity in a fully-complementary DNA three-way junction with a GC-rich branchpoint. Biochemistry, 56, pp. 4985-4991. (doi: 10.1021/acs.biochem.7b00677)

Kuznetsova, V., Southall, J., Cogdell, R. J., Fuciman, M., Polívka, T. (2017) Spectroscopic properties of the S1 state of linear carotenoids after excess energy excitation. Chemical Physics Letters, 683, pp. 448-453. (doi: 10.1016/j.cplett.2017.03.009)

Cardenas-Rodriguez, M., Tokatlidis, K. (2017) Cytosolic redox components regulate protein homeostasis via additional localisation in the mitochondrial intermembrane space. FEBS Letters, 591, pp. 2661-2670. (doi: 10.1002/1873-3468.12766)

McIntosh, A., Meikle, L. M., Ormsby, M. J., McCormick, B. A., Christie, J. M., Brewer, J. M., Roberts, M., Wall, D. M. (2017) SipA activation of caspase-3 is a decisive mediator of host cell survival at early stages of Salmonella enterica serovar typhimurium Infection. Infection and Immunity, 85, (doi: 10.1128/IAI.00393-17)

Olorunniji, F. J., McPherson, A. L., Rosser, S. J., Smith, M. C.M., Colloms, S. D., Stark, W. M. (2017) Control of serine integrase recombination directionality by fusion with the directionality factor. Nucleic Acids Research, 45, pp. 8635-8645. (doi: 10.1093/nar/gkx567)

Petersen, J., Inoue, S.-i., Kelly, S. M., Sullivan, S., Kinoshita, T., Christie, J. M. (2017) Functional characterization of a constitutively active kinase variant of Arabidopsis phototropin 1. Journal of Biological Chemistry, 292, pp. 13843-13852. (doi: 10.1074/jbc.M117.799643)

Duan, H.-G., Prokhorenko, V. I., Cogdell, R. J., Ashraf, K., Stevens, A. L., Thorwart, M., Miller, R.J. D. (2017) Nature does not rely on long-lived electronic quantum coherence for photosynthetic energy transfer. Proceedings of the National Academy of Sciences of the United States of America, 114, pp. 8493-8498. (doi: 10.1073/pnas.1702261114)

Spies, M., Smith, B. O. (2017) Protein-nucleic acids interactions: new ways of connecting structure, dynamics and function. Biophysical Reviews, 9, pp. 289-291. (doi: 10.1007/s12551-017-0284-4)

MacPherson, L., Tokatlidis, K. (2017) Protein trafficking in the mitochondrial intermembrane space: mechanisms and links to human disease. Biochemical Journal, 474, pp. 2533-2545. (doi: 10.1042/BCJ20160627)

Armfield, K., Wilson, J.B. (2017) Development of Therapeutic Approaches to Targeting EBV Related Disease.

Alqarni, S., Wilson, J.B. (2017) Epstein-Barr Virus Nuclear Antigen-1, Action and Reaction as an Oncogene.

Cai, S., Papanatsiou, M., Blatt, M. R., Chen, Z.-H. (2017) Speedy grass stomata: emerging molecular and evolutionary features. Molecular Plant, 10, pp. 912-914. (doi: 10.1016/j.molp.2017.06.002)

Kell, A., Jassas, M., Acharya, K., Hacking, K., Cogdell, R. J., Jankowiak, R. (2017) Conformational complexity in the LH2 antenna of the purple sulfur bacterium Allochromatium vinosum revealed by hole-burning spectroscopy. Journal of Physical Chemistry A, 121, pp. 4435-4446. (doi: 10.1021/acs.jpca.7b03188)

Riedelsberger, J., Blatt, M. R. (2017) Editorial: Roots—the hidden provider. Frontiers in Plant Science, 8, (doi: 10.3389/fpls.2017.01021)

Yukihira, N., Sugai, Y., Fujiwara, M., Kosumi, D., Iha, M., Sakaguchi, K., Katsumura, S., Gardiner, A. T., Cogdell, R. J., Hashimoto, H. (2017) Strategies to enhance the excitation energy-transfer efficiency in a light-harvesting system using the intra-molecular charge transfer character of carotenoids. Faraday Discussions, 198, pp. 59-71. (doi: 10.1039/c6fd00211k)

Cai, S., Chen, G., Wang, Y., Huang, Y., Marchant, B., Wang, Y., Yang, Q., Dai, F., Hills, A., Franks, P. J., Nevo, E., Soltis, D., Soltis, P., Sessa, E., Wolf, P. G., Xue, D., Zhang, G., Pogson, B. J., Blatt, M. R., Chen, Z.-H. (2017) Evolutionary conservation of ABA signaling for stomatal closure in ferns. Plant Physiology, 174, pp. 732-747. (doi: 10.1104/pp.16.01848)

Vialet-Chabrand, S., Hills, A., Wang, Y., Griffiths, H., Lew, V. L., Lawson, T., Blatt, M. R., Rogers, S. (2017) Global sensitivity analysis of OnGuard models identifies key hubs for transport interaction in stomatal dynamics. Plant Physiology, 174, pp. 680-688. (doi: 10.1104/pp.17.00170)

Morris, E. P., da Fonseca, P. C.A. (2017) High-resolution cryo-EM proteasome structures in drug development. Acta Crystallographica. Section D: Structural Biology, 73, pp. 522-533. (doi: 10.1107/S2059798317007021)

Vialet-Chabrand, S. R.M., Matthews, J. S.A., McAusland, L., Blatt, M. R., Griffiths, H., Lawson, T. (2017) Temporal dynamics of stomatal behavior: modeling and implications for photosynthesis and water use. Plant Physiology, 174, pp. 603-613. (doi: 10.1104/pp.17.00125)

Jezek, M., Blatt, M. R. (2017) The membrane transport system of the guard cell and its integration for stomatal dynamics. Plant Physiology, 174, pp. 487-519. (doi: 10.1104/pp.16.01949)

Morreale, F. E., Bortoluzzi, A., Chaugule, V. K., Arkinson, C., Walden, H., Ciulli, A. (2017) Allosteric targeting of the Fanconi anemia ubiquitin-conjugating enzyme Ube2T by fragment screening. Journal of Medicinal Chemistry, 60, pp. 4093-4098. (doi: 10.1021/acs.jmedchem.7b00147)

Kumar, A., Chaugule, V. K., Condos, T. E.C., Barber, K. R., Johnson, C., Toth, R., Sundaramoorthy, R., Knebel, A., Shaw, G. S., Walden, H. (2017) Parkin–phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nature Structural and Molecular Biology, 24, pp. 475-483. (doi: 10.1038/nsmb.3400)

Walden, H., Muqit, M. M.K. (2017) Ubiquitin and Parkinson's disease through the looking glass of genetics. Biochemical Journal, 474, pp. 1439-1451. (doi: 10.1042/BCJ20160498)

Alqarni, S., Wilson, J.B. (2017) Epstein-Barr Virus Nuclear Antigen-1, in a Preclinical Model for BL.

Armfield, K., Wilson, J.B. (2017) Therapeutic Approaches to Targeting EBV Related Disease.

Papanatsiou, M., Amtmann, A., Blatt, M. R. (2017) Stomatal clustering in Begonia associates with the kinetics of leaf gaseous exchange and influences water use efficiency. Journal of Experimental Botany, 68, pp. 2309-2315. (doi: 10.1093/jxb/erx072)

Brandani, G. B., Vance, S. J., Schor, M., Cooper, A., Kennedy, M. W., Smith, B. O., MacPhee, C. E., Cheung, D. L. (2017) Adsorption of the natural protein surfactant Rsn-2 onto liquid interfaces. Physical Chemistry Chemical Physics, 19, pp. 8584-8594. (doi: 10.1039/C6CP07261E)

Parnell, E., McElroy, S. P., Wiejak, J., Baillie, G. L., Porter, A., Adams, D. R., Rehmann, H., Smith, B. O., Yarwood, S. J. (2017) Identification of a novel, small molecule partial agonist for the cyclic AMP sensor, EPAC1. Scientific Reports, 7, (doi: 10.1038/s41598-017-00455-7)

Kritsiligkou, P., Chatzi, A., Charalampous, G., Mironov, A., Grant, C. M., Tokatlidis, K. (2017) Unconventional targeting of a thiol peroxidase to the mitochondrial intermembrane space facilitates oxidative protein folding. Cell Reports, 18, pp. 2729-2741. (doi: 10.1016/j.celrep.2017.02.053)

Mercer, I.P., Witting, T., Driver, T., Cogdell, R.J., Marangos, J.P., Tisch, J.W.G. (2017) Angle-resolved coherent wave mixing using a 4 fs ultra-broad bandwidth laser. Optics Letters, 42, pp. 859-862. (doi: 10.1364/OL.42.000859)

Cannone, G., Visentin, S., Palud, A., Henneke, G., Spagnolo, L. (2017) Structure of an octameric form of the minichromosome maintenance protein from the archaeon Pyrococcus abyssi. Scientific Reports, 7, (doi: 10.1038/srep42019)

Deschamps, T., Quentin, B., Leske, D. M., MacLeod, R., Mompelat, D., Tafforeau, L., Lotteau, V., Maréchal, V., Baillie, G. S., Gruffat, H., Wilson, J. B., Manet, E. (2017) Epstein-Barr virus nuclear antigen 1 interacts with regulator of chromosome condensation 1 dynamically throughout the cell cycle. Journal of General Virology, 98, pp. 251-265. (doi: 10.1099/jgv.0.000681)

Chen, Z.-H., Chen, G., Dai, F., Wang, Y., Hills, A., Ruan, Y.-L., Zhang, G., Franks, P. J., Nevo, E., Blatt, M. R. (2017) Molecular evolution of grass stomata. Trends in Plant Science, 22, pp. 124-139. (doi: 10.1016/j.tplants.2016.09.005)

Hayes, S., Sharma, A., Fraser, D. P., Trevisan, M., Cragg-Barber, C. K., Tavridou, E., Fankhauser, C., Jenkins, G. I., Franklin, K. A. (2017) UV-B perceived by the UVR8 photoreceptor inhibits plant thermomorphogenesis. Current Biology, 27, pp. 120-127. (doi: 10.1016/j.cub.2016.11.004)

Karnik, R., Waghmare, S., Zhang, B., Larson, E., Lefoulon, C., Gonzalez, W., Blatt, M. R. (2017) Commandeering channel voltage sensors for secretion, cell turgor, and volume control. Trends in Plant Science, 22, pp. 81-95. (doi: 10.1016/j.tplants.2016.10.006)

Manganas, P., MacPherson, L., Tokatlidis, K. (2017) Oxidative protein biogenesis and redox regulation in the mitochondrial intermembrane space. Cell and Tissue Research, 367, pp. 43-57. (doi: 10.1007/s00441-016-2488-5)

Zhang, B., Karnik, R., Waghmare, S., Donald, N. A., Blatt, M. R. (2017) VAMP721 conformations unmask an extended motif for K+ channel binding and gating control. Plant Physiology, 173, pp. 536-551. (doi: 10.1104/pp.16.01549)

Olorunniji, F. J., Merrick, C., Rosser, S. J., Smith, M. C.M., Stark, W. M., Colloms, S. D. (2017) Multipart DNA assembly using site-specific recombinases from the large serine integrase family. Springer New York

2016

Sullivan, S., Takemiya, A., Kharshiing, E., Cloix, C., Shimazaki, K.-i., Christie, J. M. (2016) Functional characterisation of Arabidopsis phototropin 1 in the hypocotyl apex. Plant Journal, 88, pp. 907-920. (doi: 10.1111/tpj.13313)

Perrella, G., Kaiserli, E. (2016) Light behind the curtain: photoregulation of nuclear architecture and chromatin dynamics in plants. New Phytologist, 212, pp. 908-919. (doi: 10.1111/nph.14269)

Li, H., Bogyo, M., da Fonseca, P. C.A. (2016) The cryo-EM structure of thePlasmodium falciparum20S proteasome and its use in the fight against malaria. FEBS Journal, 283, pp. 4238-4243. (doi: 10.1111/febs.13780)

Cupellini, L., Jurinovich, S., Campetella, M., Caprasecca, S., Guido, C. A., Kelly, S. M., Gardiner, A. T., Cogdell, R., Mennucci, B. (2016) An Ab Initio description of the excitonic properties of LH2 and their temperature dependence. Journal of Physical Chemistry B, 120, pp. 11348-11359. (doi: 10.1021/acs.jpcb.6b06585)

Nuebel, E., Manganas, P., Tokatlidis, K. (2016) Orphan proteins of unknown function in the mitochondrial intermembrane space proteome: new pathways and metabolic cross-talk. Biochimica et Biophysica Acta: Molecular Cell Research, 1863, pp. 2613-2623. (doi: 10.1016/j.bbamcr.2016.07.004)

Grinter, R., Josts, I., Mosbahi, K., Roszak, A. W., Cogdell, R. J., Bonvin, A. M.J.J., Milner, J. J., Kelly, S. M., Byron, O., Smith, B. O., Walker, D. (2016) Structure of the bacterial plant-ferredoxin receptor FusA. Nature Communications, 7, (doi: 10.1038/ncomms13308)

Bernstein, A., Sargent, E. H., Aspuru-Guzik, A., Cogdell, R., Fleming, G. R., Van Grondelle, R., Molina, M. (2016) Renewables need a grand-challenge strategy. Nature, 538, pp. 30. (doi: 10.1038/538030a)

Alpi, A. F., Chaugule, V., Walden, H. (2016) Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3. Biochemical Journal, 473, pp. 3401-3419. (doi: 10.1042/BCJ20160028)

Vialet-Chabrand, S., Matthews, J. S. A., Brendel, O., Blatt, M.R., Wang, Y., Hills, A., Griffiths, H., Rogers, S., Lawson, T. (2016) Modelling water use efficiency in a dynamic environment: an example using Arabidopsis thaliana. Plant Science, 251, pp. 65-74. (doi: 10.1016/j.plantsci.2016.06.016)

Carey, A.-M., Zhang, H., Mieritz, D., Volosin, A., Gardiner, A., Cogdell, R., Yan, H., Seo, D.-K., Lin, S., Woodbury, N. W. (2016) Photocurrent generation by photosynthetic purple bacterial reaction centers interfaced with a porous antimony-doped tin oxide (ATO) electrode. ACS Applied Materials and Interfaces, 8, pp. 25104-25110. (doi: 10.1021/acsami.6b07940)

Heilmann, M., Velanis, C. N., Cloix, C., Smith, B. O., Christie, J. M., Jenkins, G. I. (2016) Dimer/monomer status and in vivo function of salt-bridge mutants of the plant UV-B photoreceptor UVR8. Plant Journal, 88, pp. 71-81. (doi: 10.1111/tpj.13260)

Pokhilko, A., Zhao, J., Ebenhöh, O., Smith, M. C.M., Stark, W. M., Colloms, S. D. (2016) The mechanism of φC31 integrase directionality: experimental analysis and computational modelling. Nucleic Acids Research, 44, pp. 7360-7372. (doi: 10.1093/nar/gkw616)

Papanatsiou, M., Amtmann, A., Blatt, M. R. (2016) Stomatal spacing safeguards stomatal dynamics by facilitating guard cell ion transport independent of the epidermal solute reservoir. Plant Physiology, 172, pp. 254-263. (doi: 10.1104/pp.16.00850)

Morris, R. J., Brandani, G. B., Desai, V., Smith, B. O., Schor, M., MacPhee, C. E. (2016) The conformation of interfacially adsorbed Ranaspumin-2 Is an arrested state on the unfolding pathway. Biophysical Journal, 111, pp. 732-742. (doi: 10.1016/j.bpj.2016.06.006)

Löhner, A., Ashraf, K., Cogdell, R. J., Köhler, J. (2016) Fluorescence-excitation and emission spectroscopy on single FMO complexes. Scientific Reports, 6, (doi: 10.1038/srep31875)

Armfield, K., Liskamp, R., Wilson, J.B. (2016) Therapeutic Approaches to Targetting Epstein-Barr Virus Related Disease.

Maćkowski, S., Czechowski, N., Ashraf, K. U., Szalkowski, M., Lokstein, H., Cogdell, R. J., Kowalska, D. (2016) Origin of bimodal fluorescence enhancement factors of Chlorobaculum tepidumreaction centers on silver island films. FEBS Letters, 590, pp. 2558-2565. (doi: 10.1002/1873-3468.12292)

Kalef-Ezra, E., Kotzamani, D., Zaganas, I., Katrakili, N., Plaitakis, A., Tokatlidis, K. (2016) Import of a major mitochondrial enzyme depends on synergy between two distinct helices of its presequence. Biochemical Journal, 473, pp. 2813-2829. (doi: 10.1042/BCJ20160535)

Findlay, K. M.W., Jenkins, G. I. (2016) Regulation of UVR8 photoreceptor dimer/monomer photo-equilibrium in Arabidopsis plants grown under photoperiodic conditions. Plant Cell and Environment, 39, pp. 1706-1714. (doi: 10.1111/pce.12724)

Vance, S. J., Desai, V., Smith, B. O., Kennedy, M. W., Cooper, A. (2016) Aqueous solubilization of C60 fullerene by natural protein surfactants, latherin and ranaspumin-2. Biophysical Chemistry, 214-15, pp. 27-32. (doi: 10.1016/j.bpc.2016.05.003)

Chatzi, A., Manganas, P., Tokatlidis, K. (2016) Oxidative folding in the mitochondrial intermembrane space: a regulated process important for cell physiology and disease. Biochimica et Biophysica Acta: Molecular Cell Research, 1863, pp. 1298-1306. (doi: 10.1016/j.bbamcr.2016.03.023)

Ashraf, K. U., Josts, I., Mosbahi, K., Kelly, S. M., Byron, O., Smith, B. O., Walker, D. (2016) The potassium binding protein Kbp is a cytoplasmic potassium sensor. Structure, 24, pp. 741-749. (doi: 10.1016/j.str.2016.03.017)

Gawthorne, J. A., Audry, L., McQuitty, C., Dean, P., Christie, J. M., Enninga, J., Roe, A. J. (2016) Visualizing translocation and localization of bacterial type III effector proteins using a genetically encoded reporter system. Applied and Environmental Microbiology, 82, pp. 2700-2708. (doi: 10.1128/AEM.03418-15)

Buckley, A. M., Jukes, C., Candlish, D., Irvine, J. J., Spencer, J., Fagan, R. P., Roe, A. J., Christie, J., Fairweather, N. F., Douce, G. R. (2016) Lighting up Clostridium Difficile: reporting gene expression using fluorescent Lov domains. Scientific Reports, 6, (doi: 10.1038/srep23463)

Malý, P., Gruber, J. M., Cogdell, R. J., Mančal, T., van Grondelle, R. (2016) Ultrafast energy relaxation in single light-harvesting complexes. Proceedings of the National Academy of Sciences of the United States of America, 113, pp. 2934-2939. (doi: 10.1073/pnas.1522265113)

Sullivan, S., Hart, J. E., Rasch, P., Walker, C., Christie, J. (2016) Phytochrome A mediates blue-light enhancement of second-positive phototropism in Arabidopsis. Frontiers in Plant Science, 7, (doi: 10.3389/fpls.2016.00290)

Jones, D. D., Beal, J., Haddock-Angelli, T., Gershater, M., de Mora, K., Lizarazo, M., Hollenhorst, J., Rettberg, R., iGEM Interlab Study Contributors, (2016) Reproducibility of fluorescent expression from engineered biological constructs in E. coli. PLoS ONE, 11, (doi: 10.1371/journal.pone.0150182)

Modjtahedi, N., Tokatlidis, K., Dessen, P., Kroemer, G. (2016) Mitochondrial proteins containing coiled-coil-helix-coiled-coil-helix (CHCH) domains in health and disease. Trends in Biochemical Sciences, 41, pp. 245-260. (doi: 10.1016/j.tibs.2015.12.004)

Chen, Z.-H., Wang, Y., Wang, J.-W., Babla, M., Zhao, C., Garcia-Mata, C., Sani, E., Differ, C., Mak, M., Hills, A., Amtmann, A., Blatt, M. R. (2016) Nitrate reductase mutation alters potassium nutrition as well as nitric oxide-mediated control of guard cell ion channels in Arabidopsis. New Phytologist, 209, pp. 1456-1469. (doi: 10.1111/nph.13714)

Morreale, F. E., Walden, H. (2016) Types of ubiquitin ligases. Cell, 165, pp. 248-248.e1. (doi: 10.1016/j.cell.2016.03.003)

Li, H., O’Donoghue, A. J., van der Linden, W. A., Xie, S. C., Yoo, E., Foe, I. T., Tilley, L., Craik, C. S., da Fonseca, P. C.A., Bogyo, M. (2016) Structure- and function-based design of Plasmodium-selective proteasome inhibitors. Nature, 530, pp. 233-236. (doi: 10.1038/nature16936)

Ferretti, M., Hendrikx, R., Romero, E., Southall, J., Cogdell, R. J., Novoderezhkin, V. I., Scholes, G. D., van Grondelle, R. (2016) Dark states in the light-harvesting complex 2 revealed by two-dimensional electronic spectroscopy. Scientific Reports, 6, (doi: 10.1038/srep20834)

Blatt, M. R. (2016) Plant physiology: redefining the enigma of metabolism in stomatal movement. Current Biology, 26, pp. R107-R109. (doi: 10.1016/j.cub.2015.12.025)

Chaugule, V. K., Walden, H. (2016) Specificity and disease in the ubiquitin system. Biochemical Society Transactions, 44, pp. 212-227. (doi: 10.1042/BST20150209)

Magdaong, N. M., LaFountain, A. M., Hacking, K., Niedzwiedzki, D. M., Gibson, G. N., Cogdell, R., Frank, H. A. (2016) Spectral heterogeneity and carotenoid-to-bacteriochlorophyll energy transfer in LH2 light-harvesting complexes from Allochromatium vinosum. Photosynthesis Research, 127, pp. 171-187. (doi: 10.1007/s11120-015-0165-2)

Henry, S. L., Withers, J. M., Singh, I., Cooper, J. M., Clark, A. W., Burley, G. A., Cogdell, R. J. (2016) DNA-directed spatial assembly of photosynthetic light-harvesting proteins. Organic and Biomolecular Chemistry, 14, pp. 1359-1362. (doi: 10.1039/c5ob02351c)

Pokhilko, A., Zhao, J., Stark, W. M., Colloms, S. D., Ebenhöh, O. (2016) A simplified mathematical model of directional DNA site-specific recombination by serine integrases. Journal of the Royal Society: Interface, 14, (doi: 10.1098/rsif.2016.0618)

Connolly, J. P. R., Gabrielsen, M., Goldstone, R. J., Grinter, R., Wang, D., Cogdell, R. J., Walker, D., Smith, D. G. E., Roe, A. J. (2016) A highly conserved bacterial d-serine uptake system links host metabolism and virulence. PLoS Pathogens, 12, (doi: 10.1371/journal.ppat.1005359)

Minguet-Parramona, C., Wang, Y., Hills, A., Vialet-Chabrand, S., Griffiths, H., Rogers, S., Lawson, T., Lew, V. L., Blatt, M. R. (2016) An optimal frequency in Ca2+ oscillations for stomatal closure is an emergent property of ion transport in guard cells. Plant Physiology, 170, pp. 33-42. (doi: 10.1104/pp.15.01607)

Sullivan, S., Petersen, J., Blackwood, L., Papanatsiou, M., Christie, J. M. (2016) Functional characterisation of Ostreococcus tauri phototropin. New Phytologist, 209, pp. 612-623. (doi: 10.1111/nph.13640)

Hashimoto, H., Uragami, C., Cogdell, R. J. (2016) Carotenoids and Photosynthesis. Springer International Publishing

Kosumi, D., Horibe, T., Sugisaki, M., Cogdell, R. J., Hashimoto, H. (2016) Photoprotection mechanism of light-harvesting antenna complex from purple bacteria. Journal of Physical Chemistry B, 120, pp. 951-956. (doi: 10.1021/acs.jpcb.6b00121)

Wientjes, E., Renger, J., Cogdell, R., van Hulst, N. F. (2016) Pushing the photon limit: nanoantennas increase maximal photon stream and total photon number. Journal of Physical Chemistry Letters, 7, pp. 1604-1609. (doi: 10.1021/acs.jpclett.6b00491)

Merrick, C.A., Wardrope, C., Paget, J.E., Colloms, S.D., Rosser, S.J. (2016) Rapid optimization of engineered metabolic pathways with serine integrase recombinational assembly (SIRA) Elsevier

Velanis, C. N., Herzyk, P., Jenkins, G. I. (2016) Regulation of transcription by the Arabidopsis UVR8 photoreceptor involves a specific histone modification. Plant Molecular Biology, 92, pp. 425-443. (doi: 10.1007/s11103-016-0522-3)

Miki, T., Buckup, T., Krause, M. S., Southall, J., Cogdell, R. J., Motzkus, M. (2016) Vibronic coupling in the excited-states of carotenoids. Physical Chemistry Chemical Physics, 18, pp. 11443-11453. (doi: 10.1039/C5CP07542D)

2015

Kita, S., Fujii, R., Cogdell, R. J., Hashimoto, H. (2015) Characterization of fucoxanthin aggregates in mesopores of silica gel: electronic absorption and circular dichroism spectroscopies. Journal of Photochemistry and Photobiology A: Chemistry, 313, pp. 3-8. (doi: 10.1016/j.jphotochem.2015.05.009)

Hashimoto, H., Sugai, Y., Uragami, C., Gardiner, A. T., Cogdell, R. (2015) Natural and artificial light-harvesting systems utilizing the functions of carotenoids. Journal of Photochemistry and Photobiology C: Photochemistry Reviews, 25, pp. 46-70. (doi: 10.1016/j.jphotochemrev.2015.07.004)

Uragami, C., Sugai, Y., Hanjo, K., Sumino, A., Fujii, R., Nishioka, T., Kinoshita, I., Dewa, T., Nango, M., Gardiner, A. T., Cogdell, R. J., Hashimoto, H. (2015) Observation of hybrid artificial photosynthetic membranes using peripheral and core antennae from two different species of photosynthetic bacteria by AFM and fluorescence micro-spectroscopy. Journal of Photochemistry and Photobiology A: Chemistry, 313, pp. 60-71. (doi: 10.1016/j.jphotochem.2015.06.009)

Kaiserli, E., Páldi, K., O’Donnell, L., Batalov, O., Pedmale, U. V., Nusinow, D. A., Kay, S. A., Chory, J. (2015) Integration of light and photoperiodic signaling in transcriptional nuclear foci. Developmental Cell, 35, pp. 311-321. (doi: 10.1016/j.devcel.2015.10.008)

Schörner, M., Beyer, S. R., Southall, J., Cogdell, R. J., Köhler, J. (2015) Conformational memory of a protein revealed by single-molecule spectroscopy. Journal of Physical Chemistry B, 119, pp. 13964-13970. (doi: 10.1021/acs.jpcb.5b07494)

Schörner, M., Beyer, S. R., Southall, J., Cogdell, R., Köhler, J. (2015) Multi-level, multi time-scale fluorescence intermittency of photosynthetic LH2 complexes: a precursor of non-photochemical quenching? Journal of Physical Chemistry B, 119, pp. 13958-13963. (doi: 10.1021/acs.jpcb.5b06979)

Rey, B. M.F., Ibáñez, S. M., Gabrielsen, M., Franchini, G. R., Roe, A. J., Griffiths, K., Zhan, B., Cooper, A., Kennedy, M. W., Córsico, B., Smith, B. O. (2015) Diversity in the structures and ligand binding sites of nematode fatty acid and retinol binding proteins revealed by Na-FAR-1 from Necator americanus. Biochemical Journal, 471, pp. 403-414. (doi: 10.1042/BJ20150068)

Thomson, R., Smith, B. O. (2015) Solution structure of human MBD1 CXXC1. Journal of Biomolecular NMR, 63, pp. 309-314. (doi: 10.1007/s10858-015-9986-8)

Kumar, A., Aguirre, J. D., Condos, T. E.C., Martinez-Torres, R. J., Chaugule, V. K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D. E., Barber, K. R., Shaw, G. S., Walden, H. (2015) Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis. EMBO Journal, 34, pp. 2506-2521. (doi: 10.15252/embj.201592337)

Cogdell, R. J., Gardiner, A. T. (2015) Activated OCP unlocks nonphotochemical quenching in cyanobacteria. Proceedings of the National Academy of Sciences of the United States of America, 112, pp. 12547-12548. (doi: 10.1073/pnas.1517477112)

Alles, J., Hasler, D., Kazmi, S. M. A., Tesson, M., Hamilton, A., Schlegel, L., Marx, S., Eichner, N., Reinhardt, R., Meister, G., Wilson, J. B., Grässer, F. A. (2015) Epstein-Barr virus EBER transcripts affect miRNA-mediated regulation of specific targets and are processed to small RNA species. Non-Coding RNA, 1, pp. 170-191. (doi: 10.3390/ncrna1030170)

Bowyer, J., Zhao, J., Rosser, S., Colloms, S., Bates, D. (2015) Development and experimental validation of a mechanistic model of in vitro DNA recombination. (doi: 10.1109/EMBC.2015.7318519)

Joshi, A., Grinter, R., Josts, I., Chen, S., Wojdyla, J., Lowe, E., Kaminska, R., Sharp, C., McCaughey, L., Roszak, A., Cogdell, R., Byron, O., Walker, D., Kleanthous, C. (2015) Structures of the ultra-high-affinity protein–protein complexes of pyocins S2 and AP41 and their cognate immunity proteins from pseudomonas aeruginosa. Journal of Molecular Biology, 427, pp. 2852-2866. (doi: 10.1016/j.jmb.2015.07.014)

Miles, J. A., Frost, M. G., Carroll, E., Rowe, M. L., Howard, M. J., Sidhu, A., Chaugule, V. K., Alpi, A. F., Walden, H. (2015) The Fanconi Anemia DNA repair pathway is regulated by an interaction between ubiquitin and the E2-like fold domain of FANCL. Journal of Biological Chemistry, 290, pp. 20995-21006. (doi: 10.1074/jbc.M115.675835)

Kazlauskaite, A., Martinez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M.F., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H., Muqit, M. M.K. (2015) Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation. EMBO Reports, 16, pp. 939-954. (doi: 10.15252/embr.201540352)

Grefen, C., Karnik, R., Larson, E., Lefoulon, C., Wang, Y., Waghmare, S., Zhang, B., Hills, A., Blatt, M. R. (2015) A vesicle-trafficking protein commandeers Kv channel voltage sensors for voltage-dependent secretion. Nature Plants, 1, (doi: 10.1038/nplants.2015.108)

Buckley, A. M., Petersen, J., Roe, A. J., Douce, G. R., Christie, J. M. (2015) LOV-based reporters for fluorescence imaging. Current Opinion in Chemical Biology, 27, pp. 39-45. (doi: 10.1016/j.cbpa.2015.05.011)

da Fonseca, P. C.A., Morris, E. P. (2015) Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core. Nature Communications, 6, (doi: 10.1038/ncomms8573)

Fyfe, C.D., Grinter, R., Josts, I., Mosbahi, K., Roszak, A.W., Cogdell, R.J., Wall, D.M., Burchmore, R.J.S., Byron, O., Walker, D. (2015) Structure of protease-cleaved escherichia coliα-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment. Acta Crystallographica. Section D: Biological Crystallography, 71, pp. 1478-1486. (doi: 10.1107/s1399004715008548)

Hangen, E. et al. (2015) Interaction between AIF and CHCHD4 regulates respiratory chain biogenesis. Molecular Cell, 58, pp. 1001-1014. (doi: 10.1016/j.molcel.2015.04.020)

Gao, X., Wilson, J.B. (2015) LMP1: Chronic Inflammation and Carcinogenesis.

Zhang, B., Karnik, R., Wang, Y., Wallmeroth, N., Blatt, M. R., Grefen, C. (2015) The arabidopsis R-SNARE VAMP721 interacts with KAT1 and KC1 K+ channels to moderate K+ current at the plasma membrane. Plant Cell, 27, pp. 1697-1717. (doi: 10.1105/tpc.15.00305)

Papanatsiou, M., Scuffi, D., Blatt, M. R., Garia-Mata, C. (2015) Hydrogen sulphide regulates inward-rectifying K+ channels in conjunction with stomatal closure. Plant Physiology, 168, pp. 29-35. (doi: 10.1104/pp.114.256057)

Preuten, T., Blackwood, L., Christie, J. M., Fankhauser, C. (2015) Lipid anchoring of Arabidopsis phototropin 1 to assess the functional significance of receptor internalization: should I stay or should I go? New Phytologist, 206, pp. 1038-1050. (doi: 10.1111/nph.13299)

Fankhauser, C., Christie, J. M. (2015) Plant Phototropic Growth. Current Biology, 25, pp. R384-R389. (doi: 10.1016/j.cub.2015.03.020)

Parnell, E., Smith, B. O., Yarwood, S. J. (2015) The cAMP sensors, EPAC1 and EPAC2, display distinct subcellular distributions despite sharing a common nuclear pore localisation signal. Cellular Signalling, 27, pp. 989-996. (doi: 10.1016/j.cellsig.2015.02.009)

Buetow, L., Gabrielsen, M., Anthony, N. G., Dou, H., Patel, A., Aitkenhead, H., Sibbet, G. J., Smith, B. O., Huang, D. T. (2015) Activation of a primed RING E3-E2–ubiquitin complex by non-covalent ubiquitin. Molecular Cell, 58, pp. 297-310. (doi: 10.1016/j.molcel.2015.02.017)

Connolly, J. P.R., Goldstone, R. J., Burgess, K., Cogdell, R. J., Beatson, S. A., Vollmer, W., Smith, D. G.E., Roe, A. (2015) The host metabolite D-serine contributes to bacterial niche specificity through gene selection. ISME Journal, 9, pp. 1039-1051. (doi: 10.1038/ismej.2014.242)

Kaiserli, E., Chory, J. (2015) The role of phytochromes in triggering plant developmental transitions. John Wiley and Sons Ltd

Karnik, R., Zhang, B., Waghmare, S., Aderhold, C., Grefen, C., Blatt, M. R. (2015) Binding of SEC11 indicates its role in SNARE recycling after vesicle fusion and identifies two pathways for vesicular traffic to the plasma membrane. Plant Cell, 27, pp. 675-694. (doi: 10.1105/tpc.114.134429)

Shigemitsu, Y., Ikeya, T., Yamamoto, A., Tsuchie, Y., Mishima, M., Smith, B. O., Güntert, P., Ito, Y. (2015) Evaluation of the reliability of the maximum entropy method for reconstructing 3D and 4D NOESY-type NMR spectra of proteins. Biochemical and Biophysical Research Communications, 457, pp. 200-205. (doi: 10.1016/j.bbrc.2014.12.088)

Heilmann, M., Christie, J. M., Kennis, J. T.M., Jenkins, G. I., Mathes, T. (2015) Photoinduced transformation of UVR8 monitored by vibrational and fluorescence spectroscopy. Photochemical and Photobiological Sciences, 14, pp. 252-257. (doi: 10.1039/c4pp00246f)

Franchini, G. R., Pórfido, J. L., Ibáñez Shimabukuro, M., Rey Burusco, M. F., Bélgamo, J. A., Smith, B. O., Kennedy, M. W., Córsico, B. (2015) The unusual lipid binding proteins of parasitic helminths and their potential roles in parasitism and as therapeutic targets. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 93, pp. 31-36. (doi: 10.1016/j.plefa.2014.08.003)

Cannone, G., Xu, Y., Beattie, T. R., Bell, S. D., Spagnolo, L. (2015) The architecture of an Okazaki fragment-processing holoenzyme from the archaeon Sulfolobus solfataricus. Biochemical Journal, 465, pp. 239-245. (doi: 10.1042/BJ20141120)

Löhner, A., Carey, A.-M., Hacking, K., Picken, N., Kelly, S., Cogdell, R., Köhler, J. (2015) The origin of the split B800 absorption peak in the LH2 complexes from Allochromatium vinosum. Photosynthesis Research, 123, pp. 23-31. (doi: 10.1007/s11120-014-0036-2)

Cosentino, C., Alberio, L., Gazzarrini, S., Aquila, M., Romano, E., Cermenati, S., Zuccolini, P., Petersen, J., Beltrame, M., Van Etten, J. L., Christie, J., Thiel, G., Moroni, A. (2015) Engineering of a light-gated potassium channel. Science, 348, pp. 707-710. (doi: 10.1126/science.aaa2787)

Christie, J. M., Blackwood, L., Petersen, J., Sullivan, S. (2015) Plant flavoprotein photoreceptors. Plant and Cell Physiology, 56, pp. 401-413. (doi: 10.1093/pcp/pcu196)

Mathes, T., Heilmann, M., Pandit, A., Zhu, J., Ravensbergen, J., Kloz, M., Fu, Y., Smith, B.O., Christie, J.M., Jenkins, G.I., Kennis, J.T.M. (2015) Proton-coupled electron transfer constitutes the photoactivation mechanism of the plant photoreceptor UVR8. Journal of the American Chemical Society, 137, pp. 8113-8120. (doi: 10.1021/jacs.5b01177)

Ulm, R., Jenkins, G. (2015) Q&A: How do plants sense and respond to UV-B radiation? BMC Biology, 13, (doi: 10.1186/s12915-015-0156-y)

Miyamori, T., Nakasone, Y., Hitomi, K., Christie, J. M., Getzoff, E. D., Terazima, M. (2015) Reaction dynamics of the UV-B photosensor UVR8. Photochemical and Photobiological Sciences, 14, pp. 995-1004. (doi: 10.1039/c5pp00012b)

Mordas, A., Tokatlidis, K. (2015) The MIA pathway: a key regulator of mitochondrial oxidative protein folding and biogenesis. Accounts of Chemical Research, 48, pp. 2191-2199. (doi: 10.1021/acs.accounts.5b00150)

Ji, H., Wang, Y., Cloix, C., Li, K., Jenkins, G. I., Wang, S., Shang, Z., Shi, Y., Yang, S., Li, X. (2015) The arabidopsis RCC1 family protein TCF1 regulates freezing tolerance and cold acclimation through modulating lignin biosynthesis. PLoS Genetics, 11, (doi: 10.1371/journal.pgen.1005471)

Beyer, S. R., Müller, L., Southall, J., Cogdell, R. J., Ullmann, G. M., Köhler, J. (2015) The open, the closed, and the empty: time-resolved fluorescence spectroscopy and computational analysis of RC-LH1 complexes from Rhodopseudomonas palustris. Journal of Physical Chemistry B, 119, pp. 1362-1373. (doi: 10.1021/jp510822k)

Dominguez, P.N., Himmelstoss, M., Michelmann, J., Lehner, F., Gardiner, A., Cogdell, R.J., Zinth, W. (2015) The primary photosynthetic energy conversion in bacterial reaction centers—stepwise electron transfer and the effect of elevated exposure levels. Springer

Singh, V.P., Westberg, M., Wang, C., Dahlberg, P.D., Gellen, T., Gardiner, A.T., Cogdell, R.J., Engel, G.S. (2015) Towards quantification of vibronic coupling in photosynthetic antenna complexes. Journal of Chemical Physics, 142, pp. 212446. (doi: 10.1063/1.4921324)

Maiuri, M., Lüer, L., Henry, S., Carey, A.-M., Cogdell, R.J., Cerullo, G., Polli, D. (2015) Ultrafast energy flow and equilibration dynamics in photosynthetic light-harvesting complexes. Springer International Publishing

Perlík, V., Seibt, J., Cranston, L. J., Cogdell, R. J., Lincoln, C. N., Savolainen, J., Šanda, F., Mančal, T., Hauer, J. (2015) Vibronic coupling explains the ultrafast carotenoid-to-bacteriochlorophyll energy transfer in natural and artificial light harvesters. Journal of Chemical Physics, 142, (doi: 10.1063/1.4919548)

Postgraduate research students

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Our research aim is to answer fundamental questions related to the structure and function of proteins involved in important biochemical processes. Major topics on this theme include:

  • how membrane proteins form structure during biogenesis
  • how proteins are trafficked to and from the cell membrane in response to insulin stimulation
  • how protein folding is influenced by redox phenomena
  • how protein homeostasis is regulated by ubiquitin

There is a strong emphasis on the determination of protein structures using X-ray crystallography, NMR and cryo-EM. Targets of these studies include photosynthetic light harvesting complexes, plant photoreceptors and large multimeric complexes involved in RNA and DNA metabolism. These structural studies are complemented by function studies aimed at elucidating molecular mechanisms of action. Our work is supported by expertise from the Structural Biology and Biophysical Characterisation Facility and the Scottish Centre for Macromolecular Imaging. Multi-omic systems approaches, including next-generation sequencing are provided through Glasgow Polyomics.

Examples of some of the structures that we have determined are illustrated below: